[HTML][HTML] Maintaining essential microtubule bundles in meter-long axons: a role for local tubulin biogenesis?

LM Pinho-Correia, A Prokop - Brain Research Bulletin, 2023 - Elsevier
Axons are the narrow, up-to-meter long cellular processes of neurons that form the
biological cables wiring our nervous system. Most axons must survive for an organism's …

Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons

RD Smrt, J Eaves-Egenes, BZ Barkho… - Neurobiology of …, 2007 - Elsevier
It is well known that Rett Syndrome, a severe postnatal childhood neurological disorder, is
mostly caused by mutations in the MECP2 gene. However, how deficiencies in MeCP2 …

Cholestane-3β, 5α, 6β-triol suppresses proliferation, migration, and invasion of human prostate cancer cells

CY Lin, C Huo, LK Kuo, RA Hiipakka, RB Jones… - PloS one, 2013 - journals.plos.org
Oxysterols are oxidation products of cholesterol. Cholestane-3β, 5α, 6β-triol (abbreviated as
triol) is one of the most abundant and active oxysterols. Here, we report that triol exhibits anti …

Colchicine blocks tubulin heterodimer recycling by tubulin cofactors TBCA, TBCB, and TBCE

S Nolasco, J Bellido, M Serna, B Carmona… - Frontiers in cell and …, 2021 - frontiersin.org
Colchicine has been used to treat gout and, more recently, to effectively prevent
autoinflammatory diseases and both primary and recurrent episodes of pericarditis. The anti …

Surfactant protein SP-D modulates activity of immune cells: proteomic profiling of its interaction with eosinophilic cells

L Mahajan, P Gautam, E Dodagatta-Marri… - Expert review of …, 2014 - Taylor & Francis
Surfactant protein D (SP-D), a C-type lectin, is known to protect against lung infection,
allergy and inflammation. Its recombinant truncated form comprising homotrimeric neck and …

Role of cofactors B (TBCB) and E (TBCE) in tubulin heterodimer dissociation

D Kortazar, ML Fanarraga, G Carranza, J Bellido… - Experimental cell …, 2007 - Elsevier
Tubulin folding cofactors B (TBCB) and E (TBCE) are α-tubulin binding proteins that,
together with Arl2 and cofactors D (TBCD), A (TBCA or p14) and C (TBCC), participate in …

Methylome-wide and meQTL analysis helps to distinguish treatment response from non-response and pathogenesis markers in schizophrenia

BK Polakkattil, NN Vellichirammal, IV Nair… - Frontiers in …, 2024 - frontiersin.org
Schizophrenia is a complex condition with entwined genetic and epigenetic risk factors,
posing a challenge to disentangle the intermixed pathological and therapeutic epigenetic …

Genome-wide DNA methylation analysis in ankylosing spondylitis identifies HLA-B* 27 dependent and independent DNA methylation changes in whole blood

P Coit, P Kaushik, L Caplan, GS Kerr, JA Walsh… - Journal of …, 2019 - Elsevier
Background and objective Ankylosing spondylitis is a chronic inflammatory disease
characterized by inflammation of the sacroiliac joints and the spine that can lead to …

Identification of potential pathogenic genes associated with osteoporosis

B Xia, Y Li, J Zhou, B Tian, L Feng - Bone & Joint Research, 2017 - boneandjoint.org.uk
Objectives Osteoporosis is a chronic disease. The aim of this study was to identify key genes
in osteoporosis. Methods Microarray data sets GSE56815 and GSE56814, comprising 67 …

Comparison of human dental follicle cells and human periodontal ligament cells for dentin tissue regeneration

Y Tian, D Bai, W Guo, J Li, J Zeng, L Yang… - Regenerative …, 2015 - Taylor & Francis
Aim: To compare the odontogenic potential of human dental follicle cells (DFCs) and
periodontal ligament cells (PDLCs). Materials & Methods: In vitro and in vivo …