Large language models in medicine

AJ Thirunavukarasu, DSJ Ting, K Elangovan… - Nature medicine, 2023 - nature.com
Large language models (LLMs) can respond to free-text queries without being specifically
trained in the task in question, causing excitement and concern about their use in healthcare …

Challenges and applications of large language models

J Kaddour, J Harris, M Mozes, H Bradley… - arXiv preprint arXiv …, 2023 - arxiv.org
Large Language Models (LLMs) went from non-existent to ubiquitous in the machine
learning discourse within a few years. Due to the fast pace of the field, it is difficult to identify …

Hyenadna: Long-range genomic sequence modeling at single nucleotide resolution

E Nguyen, M Poli, M Faizi, A Thomas… - Advances in neural …, 2024 - proceedings.neurips.cc
Genomic (DNA) sequences encode an enormous amount of information for gene regulation
and protein synthesis. Similar to natural language models, researchers have proposed …

Welcome to the era of chatgpt et al. the prospects of large language models

T Teubner, CM Flath, C Weinhardt… - Business & Information …, 2023 - Springer
The emergence of Large Language Models (LLMs) in combination with easy-to-use
interfaces such as ChatGPT, Bing Chat, and Google's Bard represent both a Herculean task …

Progen2: exploring the boundaries of protein language models

E Nijkamp, JA Ruffolo, EN Weinstein, N Naik, A Madani - Cell systems, 2023 - cell.com
Attention-based models trained on protein sequences have demonstrated incredible
success at classification and generation tasks relevant for artificial-intelligence-driven …

[HTML][HTML] The emergent role of artificial intelligence, natural learning processing, and large language models in higher education and research

T Alqahtani, HA Badreldin, M Alrashed… - Research in Social and …, 2023 - Elsevier
Artificial Intelligence (AI) has revolutionized various domains, including education and
research. Natural language processing (NLP) techniques and large language models …

The Janus effect of generative AI: Charting the path for responsible conduct of scholarly activities in information systems

A Susarla, R Gopal, JB Thatcher… - Information Systems …, 2023 - pubsonline.informs.org
The Janus Effect of Generative AI: Charting the Path for Responsible Conduct of Scholarly
Activities in Information Systems | Information Systems Research INFORMS.org Certified …

Mechanisms and pathology of protein misfolding and aggregation

N Louros, J Schymkowitz, F Rousseau - Nature Reviews Molecular Cell …, 2023 - nature.com
Despite advances in machine learning-based protein structure prediction, we are still far
from fully understanding how proteins fold into their native conformation. The conventional …

Soil microbiome engineering for sustainability in a changing environment

JK Jansson, R McClure, RG Egbert - Nature Biotechnology, 2023 - nature.com
Recent advances in microbial ecology and synthetic biology have the potential to mitigate
damage caused by anthropogenic activities that are deleteriously impacting Earth's soil …

Improving protein expression, stability, and function with ProteinMPNN

KH Sumida, R Núñez-Franco, I Kalvet… - Journal of the …, 2024 - ACS Publications
Natural proteins are highly optimized for function but are often difficult to produce at a scale
suitable for biotechnological applications due to poor expression in heterologous systems …