Advanced near‐infrared light approaches for neuroimaging and neuromodulation

H Yin, W Jiang, Y Liu, D Zhang, F Wu, Y Zhang, C Li… - …, 2023 - Wiley Online Library
Almost all physiological processes of animals are controlled by the brain, including
language, cognitive, memory, learning, emotion and so forth. Minor brain dysfunction usually …

Nano-biosensors to detect beta-amyloid for Alzheimer's disease management

A Kaushik, RD Jayant, S Tiwari, A Vashist… - Biosensors and …, 2016 - Elsevier
Abstract Beta-amyloid (β-A) peptides are potential biomarkers to monitor Alzheimer's
diseases (AD) for diagnostic purposes. Increased β-A level is neurotoxic and induces …

Brain imaging with near-infrared fluorophores

H Wang, X Mu, J Yang, Y Liang, XD Zhang… - Coordination Chemistry …, 2019 - Elsevier
As the centralized control system of the body, the brain is a complex organ of the utmost
importance that even the most minor disorder and trauma can cause inestimable harm …

An Integrated Nanoplatform via Dual Channel Excitation for Both Precise Fluorescence Imaging and Photodynamic Therapy of Orthotopic Breast Tumor in NIR‐II …

K Lv, H Wang, X Fu, S Chen, R Zhang, Y Zhou, J Feng… - Small, 2024 - Wiley Online Library
Although research on photodynamic therapy (PDT) of malignant tumor has made
considerable progress in recent years, it is a remaining challenge to extend PDT to the …

An excellent electrochemical aptasensor for amyloid-β oligomers based on a triple-helix aptamer switch via target-triggered signal transduction DNA displacement …

X Wang, X Gu, L Li, B Yu, L Lv, Q Chen… - Analytical and Bioanalytical …, 2021 - Springer
An excellent aptasensor for electrochemical detection of amyloid-β oligomers (AβOs) at
trace levels was fabricated based on a triple-helix aptamer switch (THAS) via target …

Advances in detection methods of β-amyloid protein

M JIANG, W Xiao-Ying, W Xiao-Bing - Chinese Journal of Analytical …, 2018 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease with unknown etiology. β-amyloid
protein (Aβ) is one of the specific biomarkers of AD, and many clinical studies suggest that …

Development of Off‐On Near‐Infrared Fluorescent Probes for Sensitive In Vivo Imaging of Amyloid‐β Species with Enhanced Pharmacokinetic

Q Liu, Y Men, D Fang, Y Miao, D Ye… - Chemistry–A European … - Wiley Online Library
The fluorescent imaging of pathologically accumulated β‐amyloid (Aβ) proteins is of
significant importance to the diagnosis of Alzheimer's disease (AD). In the paper, we …

Structural Insights on Aggregation Species of Aβ and Tau, and Their Implications in Alzheimer's Disease

D Li, C Liu - 2022 - books.rsc.org
Abnormal protein aggregation has been commonly observed in a variety of
neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) …

Molecular Probes for the Diagnosis of Alzheimer's Disease with Implications for Multiplexed and Multimodal Strategies

M Ramesh, S Samanta, T Govindaraju - 2022 - books.rsc.org
AD was described a century ago with a pathological lesion of amyloid plaques accumulated
in the brain. Amyloid plaques of Aβ and neurofibrillary tangles (NFTs) of tau are the two …