Autophagy modulates cell fate decisions during lineage commitment

K Sharma, NT Asp, S Harrison, R Siller… - Autophagy, 2022 - Taylor & Francis
Early events during development leading to exit from a pluripotent state and commitment
toward a specific germ layer still need in-depth understanding. Autophagy has been shown …

[HTML][HTML] Suppression of microRNA-205-5p in human mesenchymal stem cells improves their therapeutic potential in treating diabetic foot disease

L Zhu, G Wang, S Fischbach, X Xiao - Oncotarget, 2017 - ncbi.nlm.nih.gov
Diabetes is a prevalent disease endangering human health, while diabetic foot disease (DF)
is one of the most severe complications of diabetes. Mesenchymal stem cells (MSCs) have …

Methods and systems for converting precursor cells into gastric tissues through directed differentiation

JM Wells, KW Mccracken - US Patent 10,174,289, 2019 - Google Patents
7, 704, 738 B2 7, 776, 592 B2 7. 985, 585 B2 7, 993, 916 B2 8, 187, 878 B2 8, 216, 826 B2
8, 216, 836 B2 8, 298, 822 B2 8, 318, 492 B2 8, 501, 476 B2 8, 586, 357 B2 8, 603, 809 B2 …

[HTML][HTML] Mesenchymal stem cells rejuvenate cardiac muscle through regulating macrophage polarization

B Zhang, N Zhao, J Zhang, YU Liu, D Zhu… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
We have shown that the effects of transplantation of CD146+ mesenchymal stem cells
(MSCs) on myocardial regeneration after myocardial infarction (MI) exceeds the effects of …

[HTML][HTML] Mesenchymal stem cells rejuvenate cardiac muscle after ischemic injury

B Zhang, J Zhang, D Zhu, Y Kong - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Previous studies have shown that transplantation of mesenchymal stem cells (MSCs)
enhances myocardial regeneration after myocardial infarction (MI), primarily resulting from …

[HTML][HTML] Improvement of therapeutic effects of mesenchymal stem cells in myocardial infarction through genetic suppression of microRNA-142

LX Yang, CL Wei, ML Guo, Y Zhang, F Bai, SG Ma - Oncotarget, 2017 - ncbi.nlm.nih.gov
Transplanted mesenchymal stem cells (MSCs) have been shown to contribute to myocardial
repair after myocardial infarction (MI), primarily through production and secretion some …

Methods and systems for converting precursor cells into intestinal tissues through directed differentiation

JM Wells, AM Zorn, JR Spence, NF Shroyer - US Patent 10,781,425, 2020 - Google Patents
2017-07-07 Assigned to CHILDREN'S HOSPITAL MEDICAL CENTER reassignment
CHILDREN'S HOSPITAL MEDICAL CENTER ASSIGNMENT OF ASSIGNORS INTEREST …

Methods and systems for converting precursor cells into gastric tissues through directed differentiation

JM Wells, KW Mccracken - US Patent 11,053,477, 2021 - Google Patents
US11053477B2 - Methods and systems for converting precursor cells into gastric tissues
through directed differentiation - Google Patents US11053477B2 - Methods and systems for …

Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same

J Wells, K McCracken - US Patent 11,066,650, 2021 - Google Patents
The instant disclosure relates to methods for converting mammalian definitive endoderm
(DE) cells into specific tissue (s) or organ (s) through directed differentiation. In particular, the …

[PDF][PDF] An investigation of the sterile inflammatory response in cardiac transplantation

C Nanayakkara - 2022 - research-repository.uwa.edu.au
Sterile inflammation is an understudied consequence of solid organ transplant surgery,
which contributes to intragraft inflammation. Acute allograft rejection, which remains a major …