Genomics and proteomics in liver fibrosis and cirrhosis

RA Hannivoort, V Hernandez-Gea… - Fibrogenesis & Tissue …, 2012 - Springer
Genomics and proteomics have become increasingly important in biomedical science in the
past decade, as they provide an opportunity for hypothesis-free experiments that can yield …

Development of lateral flow assay based on size-controlled gold nanoparticles for detection of hepatitis B surface antigen

DS Kim, YT Kim, SB Hong, J Kim, NS Heo, MK Lee… - Sensors, 2016 - mdpi.com
In this study, we developed lateral flow assay (LFA) biosensors for the detection of hepatitis
B surface antigens using well-controlled gold nanoparticles (AuNPs). To enhance …

[PDF][PDF] Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro

SD Woodhouse, R Narayan, S Latham, S Lee… - …, 2010 - Wiley Online Library
Hepatitis C virus (HCV) is a major cause of liver disease but the full impact of HCV infection
on the hepatocyte is poorly understood. RNA sequencing (RNA‐Seq) is a novel method to …

Proteomic analysis of plasma membranes isolated from undifferentiated and differentiated HepaRG cells

I Sokolowska, C Dorobantu, AG Woods, A Macovei… - Proteome science, 2012 - Springer
Liver infection with hepatitis B virus (HBV), a DNA virus of the Hepadnaviridae family, leads
to severe disease, such as fibrosis, cirrhosis and hepatocellular carcinoma. The early steps …

Proteomic analysis of HBV-associated HCC: insights on mechanisms of disease onset and biomarker discovery

D Niu, H Feng, WN Chen - Journal of Proteomics, 2010 - Elsevier
The development of hepatocellular carcinoma (HCC) can be considered as an end-stage
outcome of chronic hepatitis B virus (HBV) infection. Early prognostic markers are needed to …

Differential proteome analysis of host cells infected with porcine circovirus type 2

X Zhang, J Zhou, Y Wu, X Zheng, G Ma… - Journal of Proteome …, 2009 - ACS Publications
Porcine circovirus type 2 (PCV2) is the primary causative agent of postweaning
multisystemic wasting syndrome, which is an emerging swine immunosuppressive disease …

Two-dimensional liquid chromatography–tandem mass spectrometry coupled with isobaric tags for relative and absolute quantification (iTRAQ) labeling approach …

Q Lu, J Bai, L Zhang, J Liu, Z Jiang… - Journal of proteome …, 2012 - ACS Publications
Porcine reproductive and respiratory syndrome (PRRS) has devastated the pig industry
worldwide for almost 25 years, and its virus (PRRSV) preferentially infects and replicates in …

An altered pattern of liver apolipoprotein AI isoforms is implicated in male chronic hepatitis B progression

F Yang, Y Yin, F Wang, L Zhang… - Journal of proteome …, 2010 - ACS Publications
Chronic hepatitis B (CHB) appears to progress more rapidly in males than in females, and
CHB-related hepatic cirrhosis and hepatocellular carcinoma are predominately diseases …

Two-dimensional liquid chromatography–tandem mass spectrometry coupled with isobaric tags for relative and absolute quantification (iTRAQ) labeling approach …

J Liu, J Bai, Q Lu, L Zhang, Z Jiang, JJ Michal, Q He… - Journal of …, 2013 - Elsevier
Porcine circovirus type 2 (PCV2) has been identified as the essential causal agent of
postweaning multisystemic wasting syndrome, which has spread worldwide. Monocyte …

Protein profile in HBx transfected cells: a comparative iTRAQ-coupled 2D LC-MS/MS analysis

H Feng, X Li, D Niu, WN Chen - Journal of proteomics, 2010 - Elsevier
The x protein of HBV (HBx) has been involved in the development of hepatocellular
carcinoma (HCC), with a possible link to individual genotypes. Nevertheless, the underlying …