Ligament and tendon injuries are common problems in orthopedics. There is a need for
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …

Tendon-bone insertion injuries such as rotator cuff and anterior cruciate ligament injuries
are currently highly common and severe. The key method of treating this kind of injury is the …

Rotator cuff (RC) attaches to humerus across a triphasic yet continuous tissue zones (bone-
fibrocartilage-tendon), termed “enthesis”. Regrettably, rapid and functional enthesis …

Reducing rotator cuff failure after repair remains a challenge due to suboptimal tendon-to-
bone healing. In this study we report a novel biomaterial with engineered tendon …

Purpose To compare the potency of mesenchymal stem cells between the cells derived from
the subacromial bursa to concentrated bone marrow aspirate (cBMA) taken from patients …

Background Tendons are dense connective tissues and critical components for the integrity
and function of the musculoskeletal system. Tendons connect bone to muscle and transmit …

The long-term success of surgical repair of rotator cuff tears is largely dependent on
restoration of a functional tendon-to-bone interface. We implemented micro-precise …

Outcomes after repair of chronic rotator cuff injuries remain suboptimal. Type-1 collagen-rich
tendon hydrogel was previously reported to improve healing in a rat chronic rotator cuff …

Rotator cuff tear is one of the most common shoulder problems encountered by orthopedic
surgeons. Due to the slow healing process and high retear rate, rotator cuff tear has …

Fibrosis is driven by a misdirected cell response causing the overproduction of extracellular
matrix and tissue dysfunction. Numerous pharmacological strategies have attempted to …