Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐and aging‐related diseases

AG Panossian, T Efferth, AN Shikov… - Medicinal research …, 2021 - Wiley Online Library
Adaptogens comprise a category of herbal medicinal and nutritional products promoting
adaptability, resilience, and survival of living organisms in stress. The aim of this review was …

Understanding adaptogenic activity: specificity of the pharmacological action of adaptogens and other phytochemicals

A Panossian - Annals of the New York Academy of Sciences, 2017 - Wiley Online Library
Adaptogens are stress‐response modifiers that increase an organism's nonspecific
resistance to stress by increasing its ability to adapt and survive. The classical reductionist …

Rhodiola species: A comprehensive review of traditional use, phytochemistry, pharmacology, toxicity, and clinical study

H Tao, X Wu, J Cao, Y Peng, A Wang… - Medicinal Research …, 2019 - Wiley Online Library
Rhodiola species, belonging to the family Crassulaceae, have long been used as an
adaptogen, tonic, antidepressant, and antistress medicine or functional food in Asia and …

Rhodiola rosea L.: an Herb with Anti-Stress, Anti-Aging, and Immunostimulating Properties for Cancer Chemoprevention

Y Li, V Pham, M Bui, L Song, C Wu, A Walia… - Current pharmacology …, 2017 - Springer
Abstract Purpose of Review Rhodiola rosea extracts have been used as a dietary
supplement in healthy populations, including athletes, to nonspecifically enhance the …

Rhodiola rosea: a therapeutic candidate on cardiovascular diseases

Y Chen, M Tang, S Yuan, S Fu, Y Li, Y Li… - Oxidative Medicine …, 2022 - Wiley Online Library
Cardiovascular diseases, also known as circulatory diseases, are diseases of the heart and
blood vessels, and its etiology is hyperlipidemia, thick blood, atherosclerosis, and …

Natural compounds with anti-ageing activity

A Argyropoulou, N Aligiannis, IP Trougakos… - Natural product …, 2013 - pubs.rsc.org
Covering: up to the end of June 2013 Ageing is a complex molecular process driven by
diverse molecular pathways and biochemical events that are promoted by both …

Combinatorial interventions in aging

AA Parkhitko, E Filine, M Tatar - Nature Aging, 2023 - nature.com
Insight on the underlying mechanisms of aging will advance our ability to extend healthspan,
treat age-related pathology and improve quality of life. Multiple genetic and pharmacological …

Therapeutic potential and molecular mechanisms of salidroside in ischemic diseases

J Han, L Luo, Y Wang, S Wu, V Kasim - Frontiers in Pharmacology, 2022 - frontiersin.org
Rhodiola is an ancient wild plant that grows in rock areas in high-altitude mountains with a
widespread habitat in Asia, Europe, and America. From empirical belief to research studies …

[HTML][HTML] Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men

E Jówko, J Sadowski, B Długołęcka, D Gierczuk… - Journal of sport and …, 2018 - Elsevier
Purpose The objective of this study was to investigate the effects of chronic Rhodiola rosea
(R. rosea) supplementation on mental and physical performance, as well as hormonal and …

Factors that regulate expression patterns of insulin-like peptides and their association with physiological and metabolic traits in Drosophila

U Semaniuk, O Strilbytska, K Malinovska… - Insect Biochemistry and …, 2021 - Elsevier
Insulin-like peptides (ILPs) and components of the insulin signaling pathway are conserved
across different animal phyla. Eight ILPs (called DILPs) and two receptors, dInR and Lgr3 …