Olfactory circuitry and behavioral decisions

K Mori, H Sakano - Annual Review of Physiology, 2021 - annualreviews.org
In mammals, odor information detected by olfactory sensory neurons is converted to a
topographic map of activated glomeruli in the olfactory bulb. Mitral cells and tufted cells …

Behavioral and neurobiological convergence of odor, mood and emotion: A review

I Kontaris, BS East, DA Wilson - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
The affective state is the combination of emotion and mood, with mood reflecting a running
average of sequential emotional events together with an underlying internal affective state …

The subthalamic corticotropin-releasing hormone neurons mediate adaptive REM-sleep responses to threat

YT Tseng, B Zhao, S Chen, J Ye, J Liu, L Liang, H Ding… - Neuron, 2022 - cell.com
When an animal faces a threatening situation while asleep, rapid arousal is the essential
prerequisite for an adequate response. Here, we find that predator stimuli induce immediate …

Decoding the olfactory map through targeted transcriptomics links murine olfactory receptors to glomeruli

KW Zhu, SD Burton, MH Nagai, JD Silverman… - Nature …, 2022 - nature.com
Sensory processing in olfactory systems is organized across olfactory bulb glomeruli,
wherein axons of peripheral sensory neurons expressing the same olfactory receptor co …

Mapping odorant sensitivities reveals a sparse but structured representation of olfactory chemical space by sensory input to the mouse olfactory bulb

SD Burton, A Brown, TP Eiting, IA Youngstrom, TC Rust… - Elife, 2022 - elifesciences.org
In olfactory systems, convergence of sensory neurons onto glomeruli generates a map of
odorant receptor identity. How glomerular maps relate to sensory space remains unclear …

Developmental regulation of olfactory circuit formation in mice

H Sakano - Development, growth & differentiation, 2020 - Wiley Online Library
In mammals, odorants induce various behavioral responses that are critical to the survival of
the individual and species. Binding signals of odorants to odorant receptors (ORs) …

A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans

LR Saraiva, F Riveros-McKay, M Mezzavilla… - Science …, 2019 - science.org
The mammalian olfactory system displays species-specific adaptations to different
ecological niches. To investigate the evolutionary dynamics of olfactory sensory neuron …

A 3D transcriptomics atlas of the mouse nose sheds light on the anatomical logic of smell

MLRT Segura, E Abou Moussa, E Garabello… - Cell Reports, 2022 - cell.com
The sense of smell helps us navigate the environment, but its molecular architecture and
underlying logic remain understudied. The spatial location of odorant receptor genes (Olfrs) …

[HTML][HTML] Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors

Y Wang, L Cao, CY Lee, T Matsuo, K Wu… - Nature …, 2018 - nature.com
Innate behaviors are genetically encoded, but their underlying molecular mechanisms
remain largely unknown. Predator odor 2, 4, 5-trimethyl-3-thiazoline (TMT) and its potent …

Detection of neuronal defensive discharge information transmission and characteristics in periaqueductal gray double-subregions using PtNP/PEDOT: PSS modified …

B Lu, P Fan, M Li, Y Wang, W Liang, G Yang… - Microsystems & …, 2023 - nature.com
Threatened animals respond with appropriate defensive behaviors to survive. It has been
accepted that midbrain periaqueductal gray (PAG) plays an essential role in the circuitry …