Insulin resistance, type 2 diabetes mellitus and associated hyperinsulinaemia can promote
the development of a specific form of cardiomyopathy that is independent of coronary artery …

Heart failure is a complex clinical syndrome, the incidence and prevalence of which is
increased in diabetes mellitus, pre-diabetes, and obesity. Although this may arise from …

Obese and diabetic individuals are at increased risk for impairments in diastolic relaxation
and heart failure with preserved ejection fraction. The impairments in diastolic relaxation are …

Hypertension (HTN) is present in more than 50% of patients with diabetes mellitus (DM) and
contributes significantly to both microvascular and macrovascular disease in DM (Fig. 1). 1 …

The global burden of diabetes mellitus and its related complications are currently increasing.
Diabetes mellitus affects the heart through various mechanisms including microvascular …

Background: Beta-adrenergic receptors are expressed in cardiomyocytes and activated by
either noradrenaline released from sympathetic synapses or circulating catecholamines …

The metabolic syndrome is a constellation of metabolic disorders including obesity,
hypertension, and insulin resistance, components which are risk factors for the development …

944 Hypertension May 2013 bioavailable nitric oxide. 15–19 The decreased bioavailability
of nitric oxide reduces endothelial-mediated vascular relaxation and promotes vascular …

Diabetes mellitus type 2 (T2DM) is a widespread chronic medical condition with prevalence
bordering on the verge of an epidemic. It is of great concern that cardiovascular disease is …

Obesity and increased free fatty acid (FFA) level are tightly linked, leading to the
development of cardiovascular disorders. Curcumin is a natural product from Curcuma …