Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …

Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …

Background: The indole framework is considered as one of the privileged structures in the
area of medicinal chemistry and drug discovery because compounds containing this …

A new series of indolylhydrazones (6) and indole-based 4-thiazolidinones (7, 8) have been
designed, synthesized and screened for in vitro antitubercular activity against …

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, responsible
for high death frequency every year all over the world. In this regard, efficient drug‐design …

Abstract Coumarin‐3‐yl‐methyl‐1, 2, 3‐triazolyl‐1, 2, 4‐triazol‐3 (4H)‐ones (8k‐z) were
synthesized via copper (I)‐catalyzed azide‐alkyne cycloaddition click chemistry. The …

Due to the unusual structure and chemical composition of the mycobacterial cell wall,
effective tuberculosis (TB) treatment is difficult, making many antibiotics ineffective and …

As part of an ongoing effort to develop new anti-tubercular agents, a series of novel indole-
fused spirochromene hybrids (7a–l) were efficiently synthesized in excellent yields by the …

Leishmaniasis is a disease which is caused by the protozoa Leishmania and is considered
the second-highest cause of death worldwide by parasitic infection. Looking for the right …