Extrasynaptic NMDA receptors in acute and chronic excitotoxicity: implications for preventive treatments of ischemic stroke and late-onset Alzheimer's disease
SP Yu, MQ Jiang, SS Shim, S Pourkhodadad… - Molecular …, 2023 - Springer
Stroke and late-onset Alzheimer's disease (AD) are risk factors for each other; the
comorbidity of these brain disorders in aging individuals represents a significant challenge …
comorbidity of these brain disorders in aging individuals represents a significant challenge …
[HTML][HTML] Memantine: updating a rare success story in pro-cognitive therapeutics
PK Tari, CG Parsons, GL Collingridge, G Rammes - Neuropharmacology, 2024 - Elsevier
The great potential for NMDA receptor modulators as druggable targets in
neurodegenerative disorders has been met with limited success. Considered one of the rare …
neurodegenerative disorders has been met with limited success. Considered one of the rare …
Multiomics Blood-Based Biomarkers Predict Alzheimer's Predementia with High Specificity in a Multicentric Cohort Study
B Souchet, A Michaïl, M Heuillet… - The Journal of …, 2024 - Springer
Background The primary criteria for diagnosing mild cognitive impairment (MCI) due to
Alzheimer's Disease (AD) or probable mild AD dementia rely partly on cognitive …
Alzheimer's Disease (AD) or probable mild AD dementia rely partly on cognitive …
[HTML][HTML] Novel regimens of phytopolyphenols with cisplatin or memantine and ZnSO4 for synergistic inhibition of growth and gingipains of the cultured Porphyromonas …
YF Huang, HW Yang, SY Lin-Shiau - Journal of Dental Sciences, 2022 - Elsevier
Abstract Background/purpose Porphyromonas gingivalis (Pg) played a keystone pathogen
not only in initiation and progression of periodontitis but also as a risk factor involved in …
not only in initiation and progression of periodontitis but also as a risk factor involved in …
Advances in Comprehensive Treatment of the Alzheimer's Disease
W Jiang - Highlights in Science, Engineering and Technology, 2023 - drpress.org
Alzheimer's disease (AD) is one of the most popular and deadly disease. In order to deal
with Alzheimer's disease, thousands of researches, studies and experiments have been …
with Alzheimer's disease, thousands of researches, studies and experiments have been …