Cuproptosis is a newly identified form of cell death driven by copper. Recently, the role of
copper and copper triggered cell death in the pathogenesis of cancers have attracted …

Recent studies found that unbalanced copper homeostasis affect tumor growth, causing
irreversible damage. Copper can induce multiple forms of cell death, including apoptosis …

Copper (Cu) plays a pivotal role in cancer progression by acting as a co-factor that regulates
the activity of many enzymes and structural proteins in cancer cells. Therefore, Cu-based …

Unprotected exposure of skin to solar ultraviolet radiation (UVR) may damage the DNA of
skin cells and can lead to skin cancer. Sunscreens are topical formulations used to protect …

Zinc diethyldithiocarbamate (Zn (DDC) 2), a disulfiram metabolite (anti-alcoholism drug), has
shown a strong anti-cancer activity in vitro. However, its application was limited by its low …

Copper (Cu), a crucial trace element in physiological processes, has garnered significant
interest for its involvement in cancer progression and potential therapeutic applications. The …

Disulfiram (DS) has been shown to have potent anti-cancer activity; however, it is also
characterised by its low water solubility and rapid metabolism in vivo. Biodegradable …

The metal complex copper diethyldithiocarbamate (CuET) induces cancer cell death by
inhibiting protein degradation and induces proteotoxic stress, making CuET a promising …

Breast cancer (BC) is the leading cause of cancer-related mortality among women globally,
affecting approximately one-quarter of all female cancer patients and accounting for one …

Disulfiram (DSF), a Food and Drug Administration (FDA)-approved drug for the treatment of
alcoholism, has been found to have antitumor activity. DSF showed better antitumor …