Safety and immunogenicity of the first Kazakh inactivated vaccine for COVID-19

A Nurpeisova, B Khairullin, R Abitaev… - Human Vaccines & …, 2022 - Taylor & Francis
This article describes the results of a preclinical safety and immunogenicity study of
QazCovid-in®, the first COVID-19 vaccine developed in Kazakhstan, on BALB/c mice, rats …

Novel vector vaccine against Brucella abortus based on influenza A viruses expressing Brucella L7/L12 or Omp16 proteins: evaluation of protection in pregnant …

K Tabynov, B Yespembetov, A Sansyzbay - Vaccine, 2014 - Elsevier
The present study provides the first information about the protection of a novel influenza viral
vector vaccine expressing the Brucella proteins ribosomal L7/L12 or Omp16 containing the …

First evaluation of an influenza viral vector based Brucella abortus vaccine in sheep and goats: Assessment of safety, immunogenicity and protective efficacy against …

K Tabynov, B Yespembetov, N Matikhan… - Veterinary …, 2016 - Elsevier
Previously we developed and evaluated a candidate influenza viral vector based Brucella
abortus vaccine (Flu-BA) administered with a potent adjuvant Montanide Gel01 in cattle …

Generation, characterization, and protective ability of mouse monoclonal antibodies against the HA of A (H1N1) influenza virus

L Wang, F Yang, Y Xiao, B Chen, F Liu… - Journal of medical …, 2022 - Wiley Online Library
Influenza virus infections pose a continuous threat to human health. Although vaccines
function as a preventive and protective tool, they may not be effective due to antigen drift or …

Pre-Clinical Safety and Immunogenicity Study of a Coronavirus Protein-Based Subunit Vaccine for COVID-19

K Shorayeva, A Nakhanov, A Nurpeisova… - Vaccines, 2023 - mdpi.com
Creating an effective and safe vaccine is critical to fighting the coronavirus infection
successfully. Several types of COVID-19 vaccines exist, including inactivated, live …

Prime-booster vaccination of cattle with an influenza viral vector Brucella abortus vaccine induces a long-term protective immune response against Brucella abortus …

K Tabynov, B Yespembetov, S Ryskeldinova, N Zinina… - Vaccine, 2016 - Elsevier
This study analyzed the duration of the antigen-specific humoral and T-cell immune
responses and protectiveness of a recently-developed influenza viral vector Brucella …

Analysis of the efficacy of an adjuvant-based inactivated pandemic H5N1 influenza virus vaccine

A Nurpeisova, M Kassenov, N Rametov, K Tabynov… - Archives of …, 2019 - Springer
This paper describes a preclinical study analyzing the immunogenicity and protective
efficacy of Kazfluvac®, an adjuvant-based inactivated pandemic influenza A/H5N1 virus …

Evaluation of neutralizing efficacy of monoclonal antibodies specific for 2009 pandemic H1N1 influenza A virus in vitro and in vivo

J Chen, B Yan, Q Chen, Y Yao, H Wang, Q Liu… - Archives of …, 2014 - Springer
Pandemic influenza A virus (H1N1) 2009 poses a serious public-health challenge
worldwide. To characterize the neutralizing epitopes of this virus, we generated a panel of …

Safety of the novel influenza viral vector Brucella abortus vaccine in pregnant heifers

K Tabynov, S Ryskeldinova, Z Kydyrbayev… - Ciência Rural, 2015 - SciELO Brasil
The present study provides the first information about the safety of a new influenza viral
vector vaccine expressing the Brucella ribosomal protein L7/L12 or Omp16 containing the …

Optimization of cultivation condition of subtype H5 flu virus

A Mailybayeva, AS Nurpeisova… - … «Вестник НАН РК …, 2020 - journals.nauka-nanrk.kz
Аннотация This study looks into optimal conditions for cultivating the recombinant strains of
subtype H5 influenza virus. The study results in establishing optimal conditions (inoculation …