Cerebral edema (CE) and resultant intracranial hypertension are associated with
unfavorable prognosis in traumatic brain injury (TBI). CE is a leading cause of in-hospital …

Traumatic brain injury (TBI) is immediate damage caused by a blow to the head resulting
from traffic accidents, falls, and sporting activity, which causes death or serious disabilities in …

Sulfonylurea receptor 1 (SUR1) is a member of the adenosine triphosphate (ATP)-binding
cassette (ABC) protein superfamily, encoded by Abcc8, and is recognized as a key mediator …

Cerebral edema is commonly associated with cerebral pathology, and the clinical
manifestation is largely related to the underlying lesioned tissue. Brain edema usually …

Traumatic brain injury (TBI) constitutes a major health problem worldwide and is a leading
cause of death and disability in individuals, contributing to devastating socioeconomic …

Traumatic brain injury (TBI) has become one of the most important causes of death and
disability worldwide. A series of neuroinflammatory responses induced after TBI are key …

Cerebral edema and contusion expansion are major determinants of morbidity and mortality
after TBI. Current treatment options are reactive, suboptimal and associated with significant …

Introduction Cerebral edema is a key contributor to death and disability in several forms of
brain injury. Current treatment options are limited, reactive, and associated with significant …

In severe traumatic brain injury (TBI), contusions often are worsened by contusion
expansion or hemorrhagic progression of contusion (HPC), which may double the original …

Introduction: Brain swelling due to edema formation is a major cause of neurological
deterioration and death in patients with large hemispheric infarction (LHI) and severe …