Although C–H functionalization is one of the simplest reactions, it requires the use of highly
active and selective catalysts. Recently, C–H-active transformations using porous materials …

Transformation of sterically hindered tertiary alkyl electrophiles under nickel-catalyzed
conditions to forge C (sp3)–C bonds and simultaneously create challenging all-carbon …

The past decade has witnessed the emergence of N-(acyloxy) phthalimides (NHPI esters)
and its derivatives at the forefront of synthetic methods facilitating the construction of diverse …

Unnatural chiral α-tertiary amino acids containing two different carbon-based substituents at
the α-carbon centre are widespread in biologically active molecules. This sterically rigid …

One of the most oft-employed methods for C–C bond formation involving the coupling of
vinyl-halides with aldehydes catalyzed by Ni and Cr (Nozaki–Hiyama–Kishi, NHK) has been …

Historically accessed through two-electron, anionic chemistry, ketones, alcohols, and
amines are of foundational importance to the practice of organic synthesis. After placing this …

Herein, we report a nickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes
through reductive decarboxylation of redox-active esters. The present reaction enables the …

Over the last several years, radical‐mediated decarboxylative cross‐coupling reactions
employing alkyl carboxylic acids have emerged as a powerful tool for the regiospecific …

Amino acids (AAs) are key structural motifs with widespread applications in organic
synthesis, biochemistry, and material sciences. Recently, with the development of milder …

The reductive cross-coupling of sp3-hybridized carbon centers represents great synthetic
values and insurmountable challenges. In this work, we report a nickel-catalyzed …