Cyclooxygenase (COX) enzymes comprise COX-1 and COX-2 isoforms and are responsible
for prostaglandin production. Prostaglandins have critical roles in the inflammation pathway …

This review provides a brief assessment of the methodological field of trifluoromethylation
and its possible impact on the development of new CF 3-containing pharmaceuticals …

Non-steroidal anti-inflammatory drugs (NSAIDs) are the competitive inhibitors of
cyclooxygenase (COX), the enzyme which mediates the bioconversion of arachidonic acid …

The innate immune system plays a dualistic role in the evolution of ischemic brain damage
and has also been implicated in ischemic tolerance produced by different conditioning …

The introduction of selective COX-2 inhibitors (so-called 'coxibs') has demonstrated
tremendous commercial success due to their claimed lower potential of serious …

Abstract Phospholipases (PLC, PLD and PLA) are essential mediators of intracellular and
intercellular signalling. They can function as phospholipid-hydrolysing enzymes that can …

Cyclooxygenase-2 is a very important physiological enzyme playing key roles in various
biological functions especially in the mechanism of pain and inflammation, among other …

Our understanding of the key players involved in the differential regulation of T‐cell
responses during inflammation, infection and auto‐immunity is fundamental for designing …

Population growth is the driving change in the search for new, alternative sources of protein.
Macroalgae (otherwise known as seaweeds) do not compete with other food sources for …

Objective: Mounting evidence suggests that inflammation is involved in the pathogenesis of
schizophrenia. This evidence implies that anti-inflammatory agents are potentially useful …