The physiological and pathological role of tissue nonspecific alkaline phosphatase beyond mineralization

S Sekaran, S Vimalraj, L Thangavelu - Biomolecules, 2021 - mdpi.com
Tissue-nonspecific alkaline phosphatase (TNAP) is a key enzyme responsible for skeletal
tissue mineralization. It is involved in the dephosphorylation of various physiological …

LncRNA MALAT1 Promotes Tumor Angiogenesis by Regulating MicroRNA-150-5p/VEGFA Signaling in Osteosarcoma: In-Vitro and In-Vivo Analyses

S Vimalraj, R Subramanian, A Dhanasekaran - Frontiers in Oncology, 2021 - frontiersin.org
The present study aims to analyze the expression of long noncoding RNA (lncRNA)
metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in human osteosarcoma …

Folate content and retention in wheat grains and wheat-based foods: Effects of storage, processing, and cooking methods

Q Liang, K Wang, I Shariful, X Ye, C Zhang - Food chemistry, 2020 - Elsevier
Folates are essential micronutrients for human health. The aim of this study was to evaluate
the effects of storage, processing and cooking methods on folate content and identify factors …

Vitamin B12, folate, homocysteine, inflammatory mediators (Interleukin-6, tumor necrosis factor-α and C-reactive protein) levels in adolescents with anxiety or …

Y Tan, L Zhou, J Huang, X Chen, Y Wu… - Neuropsychiatric …, 2023 - Taylor & Francis
Purpose To evaluate the prevalence of abnormal vitamin B12, folate, total homocysteine
(tHcy), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP) levels …

[HTML][HTML] The chemical, antioxidant and sensorial properties of milk and plant based kombucha analogues

M Czarnowska-Kujawska, M Starowicz, B Paszczyk… - LWT, 2024 - Elsevier
Novel raw materials, almond and coconut drinks, cow's milk with and without lactose (3.2
g/100 g fat), were tested for fermentation with the use of kombucha. Chemical composition …

Impact of microRNA-210 on wound healing among the patients with diabetic foot ulcer

S Pichu, S Vimalraj, V Viswanathan - PLoS One, 2021 - journals.plos.org
Aim Diabetic foot ulcer (DFU) is a major concern in diabetes and its control requires in-depth
molecular investigation. The present study aimed to screen the expression of microRNA-210 …

[HTML][HTML] Synthesis, characterization and evaluation of swelling ratio on magnetic p53-poly (MAA-co-EGDMA)@ GO-Fe3O4 (MIP@ GO-Fe3O4)-based p53 protein and …

AA Adu, YAB Neolaka, AAP Riwu, M Iqbal… - Journal of Materials …, 2020 - Elsevier
The p53 protein plays an important role by acting as a transcription factor to regulate gene
expression and its genetic mutation has been reported as the most common genetic …

Synthesis and characterization of silibinin/phenanthroline/neocuproine copper (II) complexes for augmenting bone tissue regeneration: an in vitro analysis

S Rajalakshmi, S Vimalraj, S Saravanan… - JBIC Journal of …, 2018 - Springer
In the recent decades, flavonoid metal complexes have been widely investigated for their
multifaceted role in enabling osteoblast differentiation and bone formation. Silibinin …

The combined use of B vitamins and probiotics promotes B vitamin absorption and increases Akkermansia abundance

L Sang, S Yang, Y Zhu, Z Zhu, B Yang, Z Li, X Mao… - Food & Function, 2024 - pubs.rsc.org
B vitamins and probiotics are commonly used dietary supplements with well-documented
health benefits. However, their potential interactions remain poorly understood. This study …

Ferulic acid-Cu (II) and Zn (II) complexes promote bone formation

V Selvaraj, R Subramanian, S Sekaran… - Process …, 2021 - Elsevier
Highlights•Ferulic acid-Cu (II) and Zn (II) complexes are synthesized.•These complexes
promote osteoblast differentiation, in-vitro.•Increased co-activator and decreased co …