Polysarcosine functionalised cationic polyesters efficiently deliver self-amplifying mRNA

H Bayraktutan, RJ Kopiasz, A Elsherbeny… - Polymer …, 2024 - pubs.rsc.org
Messenger RNA (mRNA) technology is a potent platform for new vaccines and therapeutics.
To deliver RNA medicines effectively, safe delivery vectors are crucial. Among these, poly (β …

[HTML][HTML] Sparsely PEGylated poly (beta-amino ester) polyplexes enhance antigen specific T-cell response of a bivalent SARS-CoV-2 DNA vaccine

H Bayraktutan, P Symonds, VA Brentville, C Moloney… - Biomaterials, 2024 - Elsevier
DNA technology has emerged as a promising route to accelerated manufacture of sequence
agnostic vaccines. For activity, DNA vaccines must be protected and delivered to the correct …