Dendrimer-based drug delivery systems: History, challenges, and latest developments

J Wang, B Li, L Qiu, X Qiao, H Yang - Journal of Biological Engineering, 2022 - Springer
Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has
grown exponentially, from synthesis to application in the past four decades. The distinct …

Clusterization-triggered emission: Uncommon luminescence from common materials

H Zhang, Z Zhao, PR McGonigal, R Ye, S Liu… - Materials Today, 2020 - Elsevier
Abstract π-Conjugated chromophores have been investigated for many years and
successful theoretical models have been developed to explain their photophysical …

Emerging trends of nanotechnology in advanced cosmetics

SK Dubey, A Dey, G Singhvi, MM Pandey… - Colloids and surfaces B …, 2022 - Elsevier
The cosmetic industry is dynamic and ever-evolving. Especially with the introduction and
incorporation of nanotechnology-based approaches into cosmetics for evincing novel …

Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles

R De, MK Mahata, KT Kim - Advanced Science, 2022 - Wiley Online Library
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy

L Palmerston Mendes, J Pan, VP Torchilin - Molecules, 2017 - mdpi.com
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …

PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
Drug delivery systems for cancer chemotherapy are employed to improve the effectiveness
and decrease the side-effects of highly toxic drugs. Most chemotherapy agents have …

Unravelling the enigma of siRNA and aptamer mediated therapies against pancreatic cancer

Z Liu, N Parveen, U Rehman, A Aziz, A Sheikh… - Molecular Cancer, 2023 - Springer
Pancreatic cancer (PC) is a fatal disease that has a poor 5-year survival rate. The poor
prognosis can be attributed to both troublesome detections at the initial stage, which makes …

Exploring dendrimer-based drug delivery systems and their potential applications in cancer immunotherapy

S Mukherjee, S Mukherjee, MAS Abourehab… - European Polymer …, 2022 - Elsevier
Cancer immunotherapy has been researched as a major modality of treatment which
involves activating the immune system of the patient to fight against tumor cells. Dendrimers …

Cytotoxicity of dendrimers

A Janaszewska, J Lazniewska, P Trzepiński… - Biomolecules, 2019 - mdpi.com
Drug delivery systems are molecular platforms in which an active compound is packed into
or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the …

Nanotechnology-empowered strategies in treatment of skin cancer

J Chandra, N Hasan, N Nasir, S Wahab… - Environmental …, 2023 - Elsevier
In current scenario skin cancer is a serious condition that has a significant impact on world
health. Skin cancer is divided into two categories: melanoma skin cancer (MSC) and non …