Pulmonary surfactant: a unique biomaterial with life-saving therapeutic applications

B Pioselli, F Salomone, G Mazzola… - Current Medicinal …, 2022 - ingentaconnect.com
Pulmonary surfactant is a complex lipoprotein mixture secreted into the alveolar lumen by
type 2 pneumocytes, which is composed by tens of different lipids (approximately 90% of its …

The effects of different types of steroids on clinical outcomes in neonates with meconium aspiration syndrome: A systematic review, meta-analysis and GRADE …

N Phattraprayoon, T Ungtrakul, W Tangamornsuksan - Medicina, 2021 - mdpi.com
Background and Objectives: Meconium aspiration syndrome (MAS) is a condition caused by
the aspiration of meconium-stainted amniotic fluid into the lungs, resulting in pulmonary …

Efficiency of exogenous surfactant combined with intravenous N-acetylcysteine in two-hit rodent model of ARDS

M Kolomaznik, J Hanusrichterova, P Mikolka… - Respiratory Physiology …, 2023 - Elsevier
Accumulation of reactive oxygen species during hyperoxia together with secondary bacteria-
induced inflammation leads to lung damage in ventilated critically ill patients. Antioxidant N …

Approach to the connection between meconium consistency and adverse neonatal outcomes: a retrospective clinical review and prospective in vitro study

HC Fan, FW Chang, YR Pan, SI Yu, KH Chang… - Children, 2021 - mdpi.com
Whether meconium-stained amniotic fluid (MSAF) serves as an indicator of fetal distress is
under debate; however, the presence of MSAF concerns both obstetricians and …

Impact of synthetic surfactant CHF5633 with SP‐B and SP‐C analogues on lung function and inflammation in rabbit model of acute respiratory distress syndrome

P Mikolka, T Curstedt, R Feinstein… - Physiological …, 2021 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is associated with diffuse inflammation, alveolar
epithelial damage, and leakage of plasma proteins into the alveolar space, which together …

[PDF][PDF] Effects of budesonide on the lung functions, inflammation and apoptosis in a saline-lavage model of acute lung injury

D Mokra, P Kosutova, S Balentova… - J Physiol …, 2016 - researchgate.net
Diffuse alveolar injury, edema, and inflammation are fundamental signs of acute lung injury
(ALI) and acute respiratory distress syndrome (ARDS). Whereas the systemic administration …

Meconium-stained amniotic fluid during labor may be a protective factor for the offspring's childhood wheezing up to 3 years of age: the Japan Environment and …

T Murata, H Kyozuka, T Fukuda, K Imaizumi… - European Journal of …, 2022 - Springer
We aimed to evaluate the association between meconium-stained amniotic fluid during
labor and offspring's childhood wheezing. This study analyzed the data of participants …

Thrombosis density ratio can predict the occurrence of pulmonary embolism and post-thrombotic syndrome in lower-extremity deep vein thrombosis patients

MM Yao, TT Lin, X Shi, MG Chen… - Clinical …, 2024 - journals.sagepub.com
OBJECTIVE: Deep vein thrombosis (DVT) formation of lower extremities can lead to serious
complications including pulmonary embolism (PE) and chronic post-thrombotic syndrome …

Thermodynamic and Structural Study of Budesonide—Exogenous Lung Surfactant System

A Keshavarzi, A Asi Shirazi, R Korfanta… - International Journal of …, 2024 - mdpi.com
The clinical benefits of using exogenous pulmonary surfactant (EPS) as a carrier of
budesonide (BUD), a non-halogenated corticosteroid with a broad anti-inflammatory effect …

[PDF][PDF] Performance evaluation of histone deacetylases in lungs of mice exposed to ovalbumin aerosols

XM Su, Y Ren, ML Li, X Zhao, LF Kong, J Kang - J Physiol Pharmacol, 2018 - jpp.krakow.pl
This study was to investigate expression levels and functional activities of histone
deacetylases (HDACs) with potential therapeutic targets selected in animal model of allergic …