The current state of peptide drug discovery: back to the future?

A Henninot, JC Collins, JM Nuss - Journal of medicinal chemistry, 2018 - ACS Publications
Over the past decade, peptide drug discovery has experienced a revival of interest and
scientific momentum, as the pharmaceutical industry has come to appreciate the role that …

[HTML][HTML] Gastrointestinal neuroendocrine tumors in 2020

M Ahmed - World journal of gastrointestinal oncology, 2020 - ncbi.nlm.nih.gov
Gastrointestinal neuroendocrine tumors are rare slow-growing tumors with distinct
histological, biological, and clinical characteristics that have increased in incidence and …

[HTML][HTML] Gastroenteropancreatic neuroendocrine neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

M Pavel, K Öberg, M Falconi, EP Krenning, A Sundin… - Annals of …, 2020 - Elsevier
Neuroendocrine neoplasms (NENs) arise from the diffuse neuroendocrine cell system and
may occur at many different disease sites. Most frequently, these neoplasms occur in the …

ENETS consensus guidelines update for the management of patients with functional pancreatic neuroendocrine tumors and non-functional pancreatic neuroendocrine …

M Falconi, B Eriksson, G Kaltsas, DK Bartsch… - …, 2016 - karger.com
Only advances that occurred from 2011 to 2014 that either strengthen the previous 2011
guidelines [1, 2] or lead to changes or additional guidelines are reviewed here. Advances …

ENETS consensus guidelines update for the management of distant metastatic disease of intestinal, pancreatic, bronchial neuroendocrine neoplasms (NEN) and NEN …

M Pavel, D O''Toole, F Costa, J Capdevila… - …, 2016 - karger.com
M. Pavel a D. O'Toole b F. Costa c J. Capdevila d D. Gross e R. Kianmanesh f E. Krenning g
U. Knigge h R. Salazar i U.-F. Pape a K. Öberg j all other Vienna Consensus Conference …

Long-Term Efficacy, Survival, and Safety of [177Lu-DOTA0,Tyr3]octreotate in Patients with Gastroenteropancreatic and Bronchial Neuroendocrine Tumors

T Brabander, WA van der Zwan, JJM Teunissen… - Clinical Cancer …, 2017 - AACR
Purpose: Bronchial and gastroenteropancreatic neuroendocrine tumors (NET) are slow-
growing tumors, which frequently express somatostatin receptors on their cell membranes …

NCCN guidelines insights: neuroendocrine and adrenal tumors, version 2.2018

MH Shah, WS Goldner, TR Halfdanarson… - Journal of the National …, 2018 - jnccn.org
The NCCN Guidelines for Neuroendocrine and Adrenal Tumors provide recommendations
for the management of adult patients with neuroendocrine tumors (NETs), adrenal gland …

The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours

JJ Zaknun, L Bodei, J Mueller-Brand, ME Pavel… - European journal of …, 2013 - Springer
Peptide receptor radionuclide therapy (PRRNT) is a molecularly targeted radiation therapy
involving the systemic administration of a radiolabelled peptide designed to target with high …

ENETS consensus guidelines for the standards of care in neuroendocrine neoplasms: peptide receptor radionuclide therapy with radiolabelled somatostatin …

RJ Hicks, DJ Kwekkeboom, E Krenning, L Bodei… - …, 2017 - karger.com
The purpose of these guidelines is to assist physicians caring for patients with
neuroendocrine neoplasia in considering eligibility criteria for peptide receptor radionuclide …

Long-term tolerability of PRRT in 807 patients with neuroendocrine tumours: the value and limitations of clinical factors

L Bodei, M Kidd, G Paganelli, CM Grana… - European journal of …, 2015 - Springer
Purpose Peptide receptor radionuclide therapy (PRRT) with 90 Y and 177 Lu provides
objective responses in neuroendocrine tumours, and is well tolerated with moderate toxicity …