The blood–brain barrier (BBB) acts as a barrier to prevent the central nervous system (CNS)
from damage by substances that originate from the blood circulation. The BBB limits drug …

Brain tumours have a poor prognosis and lack effective treatments. The blood–brain barrier
(BBB) represents a major hurdle to drug delivery to brain tumours. In some locations in the …

Stroke is one of the leading causes of mortality and morbidity worldwide. Due to its poor
prognosis, there is a major negative impact on the patients and their family's life quality …

The incidence of brain metastases (BM) in cancer patients is increasing. After diagnosis,
overall survival (OS) is poor, elicited by the lack of an effective treatment. Monoclonal …

Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults.
Although the overall incidence is less than 10 per 100,000 individuals, its poor prognosis …

Brain diseases are the most devastating problem among the world's increasingly aging
population, and the number of patients with neurological diseases is expected to increase in …

Drug formulations and suitable methods for their detection play a very crucial role in the
development of therapeutics towards degenerative neurological diseases. For diseases …

Every year, tens of millions of individuals worldwide are affected by neurodegenerative
illnesses, which are defined by the inevitable annihilation of non-specific surroundings brain …

With a significant proportion of the global population growing older (> 60 years), the low
success rates of current diagnoses for early neurodegeneration signs are disappointing …

Nanomedicines have been a major research focus in the past two decades and are
increasingly emerging in a broad range of clinical applications. However, a proper …