When a file fractures during root canal treatment there are several treatment options
available to the clinician. The definitive management should be based on a thorough …

INTRODUCTION: Bisphosphonates (BPs) are powerful drugs that inhibit bone metabolism.
Adverse side effects are rare but potentially severe such as bisphosphonate-related …

Bisphosphonates are often used to treat osteoporosis, malignant bone metastases, and
hypercalcemia. However, it can cause serious adverse reactions, bisphosphonate-related …

The use of bisphosphonate drugs has been popularised in the late 20th century for the
management of many conditions associated with abnormalities of bone turnover, particularly …

Cancer patients can suffer oral toxic effects secondary to antineoplastic therapy in the form
of radiotherapy and/or chemotherapy. This risk is conditioned by a range of factors, including …

There has been an exponential rise in the literature of osteonecrosis and its complications in
patients taking bisphosphonate drugs. Despite this increase, there is little evidence-based …

Medication-related osteonecrosis of the jaw (MRONJ) is a complication in patients who are
on anti-bone resorptive drugs. These drugs are prescribed for patients with multiple …

OBJECTIVE: To examine outcomes of vascularized bone flap reconstruction of end-stage
osteoradionecrosis of the mandible. STUDY DESIGN: Case series with planned data …

Objectives Current recommendations for safe and effective dental management are less
than optimal for some medical conditions because of limited evidence, conflicting …

Objectives The aim of this study was to assess the quality of and outline the differences
among recommendations of published clinical practice guidelines (CPGs) for the …