Long noncoding RNA: a new player of heart failure?

R Papait, P Kunderfranco, GG Stirparo… - Journal of …, 2013 - Springer
One the most important discoveries of the post-genomic era is that a large fraction of the
genome transcribes a heterogeneous population of noncoding RNAs (ncRNA). ncRNAs …

[HTML][HTML] Genomic variations in non-coding RNAs: structure, function and regulation

D Bhartiya, V Scaria - Genomics, 2016 - Elsevier
The last decade has seen tremendous improvements in the understanding of human
variations and their association with human traits and diseases. The availability of high …

lncRNASNP v3: an updated database for functional variants in long non-coding RNAs

Y Yang, D Wang, YR Miao, X Wu, H Luo… - Nucleic Acids …, 2023 - academic.oup.com
Long non-coding RNAs (lncRNAs) act as versatile regulators of many biological processes
and play vital roles in various diseases. lncRNASNP is dedicated to providing a …

Simultaneous DNA and RNA mapping of somatic mitochondrial mutations across diverse human cancers

JB Stewart, B Alaei-Mahabadi, R Sabarinathan… - PLoS …, 2015 - journals.plos.org
Somatic mutations in the nuclear genome are required for tumor formation, but the functional
consequences of somatic mitochondrial DNA (mtDNA) mutations are less understood. Here …

An update of miRNASNP database for better SNP selection by GWAS data, miRNA expression and online tools

J Gong, C Liu, W Liu, Y Wu, Z Ma, H Chen, AY Guo - Database, 2015 - academic.oup.com
MicroRNAs (miRNAs) are key regulators of gene expression involved in a broad range of
biological processes. MiRNASNP aims to provide single nucleotide polymorphisms (SNPs) …

Investigating the ACE2 polymorphisms in COVID‐19 susceptibility: An in silico analysis

N Pouladi, S Abdolahi - Molecular genetics & genomic …, 2021 - Wiley Online Library
Abstract Background Novel coronavirus (SARS‐CoV‐2) became an epidemic disease and
lead to a pneumonia outbreak first in December 2019 in Wuhan, China. The symptoms …

Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing

JH Kim, AT Dilthey, R Nagaraja, HS Lee… - Nucleic acids …, 2018 - academic.oup.com
Despite the key role of the human ribosome in protein biosynthesis, little is known about the
extent of sequence variation in ribosomal DNA (rDNA) or its pre-rRNA and rRNA products …

SNPs and somatic mutation on long non-coding RNA: new frontier in the cancer studies?

L Minotti, C Agnoletto, F Baldassari, F Corrà, S Volinia - High-throughput, 2018 - mdpi.com
In the last decade, it has been demonstrated that long non-coding RNAs (lncRNAs) are
involved in cancer development. The great majority of studies on lncRNAs report alterations …

Fluorogenic RNA-based biomaterials for imaging and tracking the cargo of extracellular vesicles

EE Bonacquisti, SW Ferguson, GM Wadsworth… - Journal of Controlled …, 2024 - Elsevier
Extracellular vesicles (EVs), or exosomes, play important roles in physiological and
pathological cellular communication and have gained substantial traction as biological drug …

Synonymous variants that disrupt messenger RNA structure are significantly constrained in the human population

JBS Gaither, GE Lammi, JL Li, DM Gordon… - …, 2021 - academic.oup.com
Background The role of synonymous single-nucleotide variants in human health and
disease is poorly understood, yet evidence suggests that this class of “silent” genetic …