Alginates are natural polysaccharides widely participating in food, pharmaceutical, and
environmental applications due to their excellent gelling capacity. Their excellent …

Because free therapeutic drug molecules often have adverse effects on normal tissues,
deliver scanty drug concentrations and exhibit a potentially low efficacy at pathological sites …

Many chronic diseases such as Alzheimer's disease, diabetes, and cardiovascular diseases
are closely related to in vivo oxidative stress caused by excessive reactive oxygen species …

Background Brain-derived neurotrophic factor (BDNF) with neuronic development and
function is a promising therapeutic agent for treating depressive disorder, according to the …

Intranasal administration has gained an increasing interest for brain drug delivery since it
allows direct transport through neuronal pathways, which can be quite advantageous for …

Background Depression is one of the most debilitating and severe psychiatric disorders and
a serious public health concern. Currently, many treatments are indicated for depression …

As a mental disease in modern society, depression shows an increasing occurrence, with
low cure rate and high recurrence rate. It has become the most disabling disease in the …

Abstract Nasal administration of Traditional Chinese medicine (TCM) has a long history of
applications. With the gradual maturing of technology and pharmacological advances, nasal …

Nanotechnology has proved its tremendous worth in the field of drug delivery and targeting.
Nano formulations have improved the safety and efficacy of various conventional drugs …

Abstract Background Genus Paeonia, which is the main source of Traditional Chinese
Medicine (TCM) Paeoniae Radix Rubra (Chishao in Chinese), Paeoniae Radix Alba …