Telomerase extends chromosome ends by iterative reverse transcription of its RNA
template. Following the addition of each telomeric repeat, the RNA template and the …

Parallel research on multiple model organisms shows that while some principles of telomere
biology are conserved among all eukaryotic kingdoms, we also find some deviations that …

The short read-length of next-generation sequencing makes it challenging to characterize
highly repetitive regions (HRRs) such as centromeres, telomeres and ribosomal DNAs …

End‐to‐end fusion of critically shortened telomeres in higher eucaryotes is presumed to be
mediated by nonhomologous end‐joining (NHEJ). Here we describe two PCR‐based …

The model for telomere shortening at each replication cycle is currently incomplete, and the
exact contribution of the telomeric 3′ overhang to the shortening rate remains unclear …

In plants, gametogenesis occurs late in development, and somatic mutations can therefore
be transmitted to the next generation. Longer periods of growth are believed to result in an …

Single-strand extensions of the G strand of telomeres are known to be critical for
chromosome-end protection and length regulation. Here, we report that in C. elegans …

Telomeres vary greatly in size among plants and, in most higher plants, consist of a long
array of 5′‐TTTAGGG‐3′/3′‐AAATCCC‐5′(TTTAGGG) repeats. Recently, telomeric …

The end replication problem hypothesis proposes that the ends of linear DNA cannot be
replicated completely during lagging strand DNA synthesis. Although the idea has been …

Single-stranded telomeric DNA protrusions are considered to be evolutionarily conserved
structural elements essential for chromosome end protection. Their formation at telomeres …