Despite tremendous successes in the field of antibiotic discovery seen in the previous
century, infectious diseases have remained a leading cause of death. More specifically …

The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

Pseudomonas aeruginosa is a Gram-negative bacterium belonging to the γ-proteobacteria.
Like other members of the Pseudomonas genus, it is known for its metabolic versatility and …

Lignin is the most abundant phenolic polymer; thus, its decomposition by microorganisms is
fundamental to carbon cycling on earth. Lignin breakdown is initiated by depolymerization …

Abstract β-barrel membrane proteins are essential for nutrient import, signalling, motility and
survival. In Gram-negative bacteria, the β-barrel assembly machinery (BAM) complex is …

Acinetobacter baumannii is an opportunistic pathogen, causing infections mainly in patients
in intensive care units where the extensive use of antimicrobial agents can select for the …

Gram-negative bacteria depend on their cell membranes for survival and environmental
adaptation. They contain two membranes, one of which is the outer membrane (OM), which …

Lipopolysaccharide (LPS) is essential for most Gram-negative bacteria and has crucial roles
in protection of the bacteria from harsh environments and toxic compounds, including …

Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …

Food wastes can be hydrolyzed into soluble microbial substrates, contributing to
sustainability. Halomonas spp.-based Next Generation Industrial Biotechnology (NGIB) …