Fungal diseases represent an important paradigm in immunology, as they can result from
either a lack of recognition by the immune system or overactivation of the inflammatory …

Racial and ethnic identities, largely understood as social rather than biologic constructs,
may impact risk for acquiring infectious diseases, including fungal infections. Risk factors …

Fungi, usually present as commensals, are a major cause of opportunistic infections in
immunocompromised patients. Such infections, if not diagnosed or treated properly, can …

Fungi are ubiquitous in our environment, and a healthy immune system is essential to
maintain adequate protection from fungal infections. When this protection breaks down …

Mannose-binding lectin (MBL) is an innate immune system pattern recognition protein that
kills a wide range of pathogenic microbes through complement activation. A substantial …

Transplant patients, including solid-organ transplant (SOT) and hematopoietic stem cell
transplant (HSCT) recipients, are exposed to various types of complications, particularly …

Fungi are the cause of opportunistic infections, predominantly in immunocompromised
individuals although, primary fungal infections can occur in apparently healthy individuals …

Background Mannose binding lectin (MBL) is an important host defence protein against
opportunistic fungal pathogens. This carbohydrate-binding protein, an opsonin and lectin …

An improved understanding of the pathogenesis of Aspergillus infections has facilitated the
identification of host biomarkers that, if validated in well-designed prospective studies, could …

Collectins are collagen-containing C-type (calcium-dependent) lectins which are important
pathogen pattern recognising innate immune molecules. Their primary structure is …