Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers
Drug repurposing is promoted as a cost-and time-effective mechanism for providing new
medicines. Often, however, there is insufficient consideration by academic researchers of …
medicines. Often, however, there is insufficient consideration by academic researchers of …
Resistance and overcoming resistance in breast cancer
A Luque-Bolivar, E Pérez-Mora… - … Cancer: Targets and …, 2020 - Taylor & Francis
The incidence and mortality of breast cancer (BC) have increased in recent years, and BC is
the main cause of cancer-related death in women worldwide. One of the most significant …
the main cause of cancer-related death in women worldwide. One of the most significant …
The lung microbiota: role in maintaining pulmonary immune homeostasis and its implications in cancer development and therapy
M Sommariva, V Le Noci, F Bianchi, S Camelliti… - Cellular and Molecular …, 2020 - Springer
Like other body districts, lungs present a complex bacteria community. An emerging function
of lung microbiota is to promote and maintain a state of immune tolerance, to prevent …
of lung microbiota is to promote and maintain a state of immune tolerance, to prevent …
The immunomodulatory effects of macrolide antibiotics in respiratory disease
J Pollock, JD Chalmers - Pulmonary Pharmacology & Therapeutics, 2021 - Elsevier
Macrolide antibiotics are well known for their antibacterial properties, but extensive research
in the context of inflammatory lung disease has revealed that they also have powerful …
in the context of inflammatory lung disease has revealed that they also have powerful …
Review on PLGA polymer based nanoparticles with antimicrobial properties and their application in various medical conditions or infections
The rise in the resistance to antibiotics is due to their inappropriate use and the use of a
broad spectrum of antibiotics. This has also contributed to the development of multidrug …
broad spectrum of antibiotics. This has also contributed to the development of multidrug …
Inhalation delivery of repurposed drugs for lung cancer: approaches, benefits and challenges
Lung cancer (LC) is one of the leading causes of mortality accounting for almost 25% of
cancer deaths throughout the world. The shortfall of affordable and effective first-line …
cancer deaths throughout the world. The shortfall of affordable and effective first-line …
[HTML][HTML] Harnessing the therapeutic potential of anticancer drugs through amorphous solid dispersions
The treatment of cancer is still a major challenge. But tremendous progress in anticancer
drug discovery and development has occurred in the last few decades. However, this …
drug discovery and development has occurred in the last few decades. However, this …
[HTML][HTML] Blockage of autophagy for cancer therapy: a comprehensive review
The incidence and mortality of cancer are increasing, making it a leading cause of death
worldwide. Conventional treatments such as surgery, radiotherapy, and chemotherapy face …
worldwide. Conventional treatments such as surgery, radiotherapy, and chemotherapy face …
Understanding breast cancer: From conventional therapies to repurposed drugs
B Costa, I Amorim, F Gärtner, N Vale - European Journal of Pharmaceutical …, 2020 - Elsevier
Breast cancer is the most common cancer among women and is considered a developed
country disease. Moreover, is a heterogenous disease, existing different types and stages of …
country disease. Moreover, is a heterogenous disease, existing different types and stages of …
The glucosinolates: a sulphur glucoside family of mustard anti-tumour and antimicrobial phytochemicals of potential therapeutic application
J Melrose - Biomedicines, 2019 - mdpi.com
This study reviewed aspects of the biology of two members of the glucosinolate family,
namely sinigrin and glucoraphanin and their anti-tumour and antimicrobial properties …
namely sinigrin and glucoraphanin and their anti-tumour and antimicrobial properties …