Exploring the role of intratendinous pressure in the pathogenesis of tendon pathology: a narrative review and conceptual framework

L Pringels, JL Cook, E Witvrouw, A Burssens… - British journal of sports …, 2023 - bjsm.bmj.com
Despite the high prevalence of tendon pathology in athletes, the underlying pathogenesis is
still poorly understood. Various aetiological theories have been presented and rejected in …

Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues

JL Zitnay, GS Jung, AH Lin, Z Qin, Y Li, SM Yu… - Science …, 2020 - science.org
Overuse injuries to dense collagenous tissues are common, but their etiology is poorly
understood. The predominant hypothesis that micro-damage accumulation exceeds the rate …

Saline-polyethylene glycol blends preserve in vitro annulus fibrosus hydration and mechanics: An experimental and finite-element analysis

B Werbner, M Zhou, N McMindes, A Lee, M Lee… - Journal of the …, 2022 - Elsevier
Precise control of tissue water content is essential for ensuring accurate, repeatable, and
physiologically relevant measurements of tissue mechanics and biochemical composition …

Assessment of the viscoelastic mechanical properties of the porcine optic nerve head using micromechanical testing and finite element modeling

BN Safa, AT Read, CR Ethier - Acta biomaterialia, 2021 - Elsevier
Optic nerve head (ONH) biomechanics is centrally involved in the pathogenesis of
glaucoma, a blinding ocular condition often characterized by elevation and fluctuation of the …

Tendons exhibit greater resistance to tissue and molecular-level damage with increasing strain rate during cyclic fatigue

JL Zitnay, AH Lin, JA Weiss - Acta biomaterialia, 2021 - Elsevier
Musculoskeletal soft connective tissues are commonly injured due to repetitive use, but the
evolution of mechanical damage to the tissue structure during repeated loading is poorly …

On the contribution of solid and fluid behavior to the modeling of the time-dependent mechanics of tendons under semi-confined compression

B Klahr, JZ Lanzendorf, JLM Thiesen, OT Pinto… - Journal of the …, 2023 - Elsevier
The present work aims to investigate whether it is possible to identify and quantify the
contributions of the interstitial fluid and the solid skeleton to the overall time-dependent …

Second-order computational homogenization for bridging poromechanical scales under large deformations

JLM Thiesen, B Klahr, TA Carniel, GA Holzapfel… - Computer Methods in …, 2025 - Elsevier
We introduce a second-order computational homogenization procedure designed to
address heterogeneous poromechanical media. Our approach relies on the method of …

Global and local identifiability analysis of a nonlinear biphasic constitutive model in confined compression

JM Peloquin, DM Elliott - Journal of the Royal Society …, 2024 - royalsocietypublishing.org
Application of biomechanical models relies on model parameters estimated from
experimental data. Parameter non-identifiability, when the same model output can be …

Degree of twist in the Achilles tendon interacts with its length and thickness in affecting local strain magnitude: a finite element analysis

S Enomoto, S Furuuchi, T Ishibashi… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction The relationship between the twisting of the three subtendons of the Achilles
tendon (AT) and local strain has received attention in recent years. The present study aimed …

Identifiability of tissue material parameters from uniaxial tests using multi-start optimization

BN Safa, MH Santare, CR Ethier, DM Elliott - Acta biomaterialia, 2021 - Elsevier
Determining tissue biomechanical material properties from mechanical test data is
frequently required in a variety of applications. However, the validity of the resulting …