Machine intelligence in peptide therapeutics: A next‐generation tool for rapid disease screening

S Basith, B Manavalan, T Hwan Shin… - Medicinal research …, 2020 - Wiley Online Library
Discovery and development of biopeptides are time‐consuming, laborious, and dependent
on various factors. Data‐driven computational methods, especially machine learning (ML) …

Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

[HTML][HTML] Cellular interactions in the tumor microenvironment: the role of secretome

BR da Cunha, C Domingos, ACB Stefanini… - Journal of …, 2019 - ncbi.nlm.nih.gov
Over the past years, it has become evident that cancer initiation and progression depends
on several components of the tumor microenvironment, including inflammatory and immune …

In silico tools and databases for designing peptide-based vaccine and drugs

SS Usmani, R Kumar, S Bhalla, V Kumar… - Advances in protein …, 2018 - Elsevier
The prolonged conventional approaches of drug screening and vaccine designing
prerequisite patience, vigorous effort, outrageous cost as well as additional manpower …

AntiTbPdb: a knowledgebase of anti-tubercular peptides

SS Usmani, R Kumar, V Kumar, S Singh… - Database, 2018 - academic.oup.com
Tuberculosis is a global menace, caused by Mycobacterium tuberculosis, responsible for
millions of premature deaths every year. In the era of drug-resistant tuberculosis, peptide …

SalivaDB—a comprehensive database for salivary biomarkers in humans

A Arora, D Kaur, S Patiyal, D Kaur, R Tomer… - Database, 2023 - academic.oup.com
Saliva as a non-invasive diagnostic fluid has immense potential as a tool for early diagnosis
and prognosis of patients. The information about salivary biomarkers is broadly scattered …

Prediction of antimicrobial potential of a chemically modified peptide from its tertiary structure

P Agrawal, GPS Raghava - Frontiers in Microbiology, 2018 - frontiersin.org
Designing novel antimicrobial peptides is a hot area of research in the field of therapeutics
especially after the emergence of resistant strains against the conventional antibiotics. In the …

PRRDB 2.0: a comprehensive database of pattern-recognition receptors and their ligands

D Kaur, S Patiyal, N Sharma, SS Usmani… - Database, 2019 - academic.oup.com
PRRDB 2.0 is an updated version of PRRDB that maintains comprehensive information
about pattern-recognition receptors (PRRs) and their ligands. The current version of the …

Nanopore discrimination of coagulation biomarker derivatives and characterization of a post-translational modification

A Stierlen, SJ Greive, L Bacri, P Manivet, B Cressiot… - Biophysical …, 2023 - cell.com
One of the most critical health challenges is sensitive early and ongoing disease detection
for prevention and personalized treatment management. Developing new sensitive …

CancerLivER: a database of liver cancer gene expression resources and biomarkers

H Kaur, S Bhalla, D Kaur, GPS Raghava - Database, 2020 - academic.oup.com
Liver cancer is the fourth major lethal malignancy worldwide. To understand the
development and progression of liver cancer, biomedical research generated a tremendous …