Childhood sarcoidosis is a rare multisystemic granulomatous disorder of unknown etiology.
In the pediatric series reported from the southeastern United States, sarcoidosis had a …

Sarcoidosis is characterized by intense inflammation at the different sites of localization.
Many different mediators, such as cytokines, chemokines, and other proteins with various …

Background Sarcoidosis is a multisystem granulomatous disease of unknown etiology. No
suitable biomarkers are available to evaluate the evolution of this disease, which still has an …

Sarcoidosis is an uncommon disease of granulomatous inflammation. Genetic
predisposition to sarcoidosis is indicated by observations of familial clustering, increased …

Background Sarcoidosis is a multisystemic inflammatory granulomatous disease of
unknown etiology. No suitable biomarkers are available to evaluate the prognosis of this …

Background Pulmonary sarcoidosis involves an intense leukocyte infiltration of the lung with
the formation of non-necrotizing granulomas. CC chemokines (chemokine (CC motif) ligand …

BACKGROUND: In previous papers, we found significantly higher activity of chitotriosidase,
a macrophage derived enzyme, in serum and BAL of patients with sarcoidosis, especially in …

MicroRNAs (miRNAs) act as post-transcriptional regulators of gene expression. In
sarcoidosis, aberrant miRNA expression may enhance immune responses mounted against …

Purpose: High-mobility group box-1 (HMGB1) is a nonhistone DNA-binding nuclear protein
released from necrotic cells, which is also secreted by activated leukocytes and acts as a …

The objective of this study was to assess protein levels for candidate cytokines, chemokines,
growth factors, matrix metalloproteinases and their inhibitors in bronchoalveolar lavage fluid …