Neuroimaging detectable differences between Parkinson's disease motor subtypes: a systematic review

JT Boonstra, S Michielse, Y Temel… - Movement disorders …, 2021 - Wiley Online Library
Background The neuroanatomical substrates of Parkinson's disease (PD) with tremor‐
dominance (TD) and those with non‐tremor dominance (nTD), postural instability and gait …

Cerebral small vessel disease may worsen motor function, cognition, and mood in Parkinson's disease

H Chen, H Wan, M Zhang, G Liu, X Wang… - Parkinsonism & Related …, 2021 - Elsevier
Introduction Emerging evidence has suggested that cerebral small vessel disease (CSVD)
may worsen motor function and cognition in Parkinson's disease (PD). However, the effect of …

Auto-classification of Parkinson's disease with different motor subtypes using arterial spin labelling MRI based on machine learning

J Xiong, H Zhu, X Li, S Hao, Y Zhang, Z Wang, Q Xi - Brain sciences, 2023 - mdpi.com
The purpose of this study was to automatically classify different motor subtypes of
Parkinson's disease (PD) on arterial spin labelling magnetic resonance imaging (ASL-MRI) …

Plasma exosomal brain-derived neurotrophic factor correlated with the postural instability and gait disturbance–Related motor symptoms in patients with Parkinson's …

CC Chung, PH Huang, L Chan, JH Chen, LN Chien… - Diagnostics, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is an essential neurotrophin, responsible for
neuronal development, function, and survival. Assessments of peripheral blood BDNF in …

Basal ganglia and brainstem located cerebral microbleeds contributed to gait impairment in patients with cerebral small vessel disease

HJ Mao, JX Zhang, WC Zhu, H Zhang… - Journal of …, 2023 - content.iospress.com
Background: The mechanism of gait disorder in patients with cerebral small vessel disease
(CSVD) remains unclear. Limited studies have compared the effect of cerebral microbleeds …

The challenging quest of neuroimaging: From clinical to molecular-based subtyping of Parkinson disease and atypical parkinsonisms

S Sasikumar, AP Strafella - Handbook of Clinical Neurology, 2023 - Elsevier
The current framework of Parkinson disease (PD) focuses on phenotypic classification
despite its considerable heterogeneity. We argue that this method of classification has …

Quantitative susceptibility mapping changes relate to gait issues in Parkinson's disease

N Nathoo, M Gee, K Nelles, J Burt, H Sun… - Canadian journal of …, 2023 - cambridge.org
Background: Quantitative susceptibility mapping (QSM) demonstrates elevated iron content
in Parkinson's disease (PD) patients within the basal ganglia, though it has infrequently …

[HTML][HTML] Impact of cerebral microbleeds on gait, balance, and upper extremities function in cerebral small vessel disease

Y Hou, S Yang, Y Li, W Qin, L Yang… - Journal of Integrative …, 2023 - imrpress.com
Background and Purpose: White matter hyperintensites (WMHs), lacunes and brain atrophy
have been demonstrated to be positively related to gait disorder. However, cerebral …

Cerebral microbleeds were related with poor cognitive performances on the dual task condition in older adults

X Li, S Yang, W Qin, L Yang, Y Li, Y Hou… - Frontiers in Aging …, 2022 - frontiersin.org
Background: The dual task (DT) was commonly used to assess the risk of falls in older adults
and patients with neurological disorders. However, the performance on DT conditions has …

The performance of patients with cerebral microbleeds in different cognitive tests: A cross-sectional study

X Li, S Yang, Y Li, W Qin, L Yang, J Yuan… - Frontiers in Aging …, 2023 - frontiersin.org
Background The clinical features and pathological process of cerebral microbleed (CMB)-
related cognitive impairment are hot topics of cerebral small vessel disease (CSVD) …