Cdc42-the centre of polarity

S Etienne-Manneville - Journal of cell science, 2004 - journals.biologists.com
All cell types polarize, at least transiently, during division or to generate specialized shapes
and functions. This capacity extends from yeast to mammals, and it is now clear that many …

Cell polarization and cytokinesis in budding yeast

E Bi, HO Park - Genetics, 2012 - academic.oup.com
Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …

Central roles of small GTPases in the development of cell polarity in yeast and beyond

HO Park, E Bi - Microbiology and molecular biology reviews, 2007 - Am Soc Microbiol
The establishment of cell polarity is critical for the development of many organisms and for
the function of many cell types. A large number of studies of diverse organisms from yeast to …

Regulation of G protein–initiated signal transduction in yeast: paradigms and principles

HG Dohlman, J Thorner - Annual review of biochemistry, 2001 - annualreviews.org
▪ Abstract All cells have the capacity to evoke appropriate and measured responses to signal
molecules (such as peptide hormones), environmental changes, and other external stimuli …

GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila

A Bernards - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2003 - Elsevier
Typical members of the Ras superfamily of small monomeric GTP-binding proteins function
as regulators of diverse processes by cycling between biologically active GTP-and inactive …

[HTML][HTML] Negative feedback enhances robustness in the yeast polarity establishment circuit

AS Howell, M Jin, CF Wu, TR Zyla, TC Elston, DJ Lew - Cell, 2012 - cell.com
Many cells undergo symmetry-breaking polarization toward a randomly oriented" front" in
the absence of spatial cues. In budding yeast, such polarization involves a positive feedback …

A protein interaction map for cell polarity development

BL Drees, B Sundin, E Brazeau, JP Caviston… - The Journal of cell …, 2001 - rupress.org
Many genes required for cell polarity development in budding yeast have been identified
and arranged into a functional hierarchy. Core elements of the hierarchy are widely …

The role of Cdc42p GTPase-activating proteins in assembly of the septin ring in yeast

JP Caviston, M Longtine, JR Pringle… - Molecular biology of the …, 2003 - Am Soc Cell Biol
The septins are a conserved family of GTP-binding, filament-forming proteins. In the yeast
Saccharomyces cerevisiae, the septins form a ring at the mother-bud neck that appears to …

Ypt and Rab GTPases: insight into functions through novel interactions

N Segev - Current opinion in cell biology, 2001 - Elsevier
Ypt/Rab GTPases are key regulators of vesicular transport in eukaryotic cells. During the
past two years, a number of new Ypt/Rab-interacting proteins have been identified and …

Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p

AS Gladfelter, I Bose, TR Zyla, ESG Bardes… - The Journal of cell …, 2002 - rupress.org
At the beginning of the budding yeast cell cycle, the GTPase Cdc42p promotes the assembly
of a ring of septins at the site of future bud emergence. Here, we present an analysis of …