Reactive oxygen species (ROS), superoxide anion and hydrogen peroxide, are generated
as byproducts of oxidative phosphorylation in the mitochondria or via cell signaling-induced …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is ubiquitously expressed in most eukaryotic
cells and functions to induce a broad range of cellular defenses against exogenous and …

Background Adipose tissue-derived mesenchymal stem cells (ADSCs) are promising
candidates for regenerative medicine. However, long-term in vitro passaging leads to …

Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms
remain incompletely understood. Here, we use the intestine of Drosophila melanogaster to …

Understanding how cell fate decisions are regulated is a fundamental goal of developmental
and stem cell biology. Most studies on the control of cell fate decisions address the …

Ganoderma lucidum has received a lot of attention recently due to its medicinal potential
activities. The aim of this designed experiment was to evaluate the beneficial effects of …

Reactive oxygen species (ROS) play a key role in cell physiology and function. ROS
represents a potential source of damage for many macromolecules including DNA. It is …

Mitochondria are essential organelles that have recently emerged as hubs for several
metabolic and signaling pathways in the cell. Mitochondrial morphology is regulated by …

Pluripotent stem cells of the mammalian epiblast and their cultured counterparts—embryonic
stem cells (ESCs) and epiblast stem cells (EpiSCs)—have the capacity to differentiate in all …

Diabetic nephropathy is the leading cause of end‐stage renal disease in patients with
diabetes mellitus. Oxidative stress has been shown to play an important role in …