[HTML][HTML] Candida auris Genetics and Emergence

A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …

Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond

Y Lee, E Puumala, N Robbins, LE Cowen - Chemical reviews, 2020 - ACS Publications
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

[HTML][HTML] Candida auris: Epidemiology, biology, antifungal resistance, and virulence

H Du, J Bing, T Hu, CL Ennis, CJ Nobile… - PLoS …, 2020 - journals.plos.org
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida
auris is becoming a worldwide public health threat that has been attracting considerable …

Drug resistance and tolerance in fungi

J Berman, DJ Krysan - Nature Reviews Microbiology, 2020 - nature.com
Systemic fungal infections pose a serious clinical problem. Treatment options are limited,
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …

Tracing the evolutionary history and global expansion of Candida auris using population genomic analyses

NA Chow, JF Muñoz, L Gade, EL Berkow, X Li… - MBio, 2020 - Am Soc Microbiol
Candida auris has emerged globally as a multidrug-resistant yeast that can spread via
nosocomial transmission. An initial phylogenetic study of isolates from Japan, India …

[HTML][HTML] Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in …

S Ahmad, W Alfouzan - Microorganisms, 2021 - mdpi.com
Candida auris, a recently recognized, often multidrug-resistant yeast, has become a
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …

[HTML][HTML] The antifungal pipeline: fosmanogepix, ibrexafungerp, olorofim, opelconazole, and rezafungin

M Hoenigl, R Sprute, M Egger, A Arastehfar… - Drugs, 2021 - Springer
The epidemiology of invasive fungal infections is changing, with new populations at risk and
the emergence of resistance caused by the selective pressure from increased usage of …

[HTML][HTML] Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida auris

A Cortegiani, G Misseri, T Fasciana… - Journal of intensive …, 2018 - Springer
Candida spp. infections are a major cause of morbidity and mortality in critically ill patients.
Candida auris is an emerging multi-drug-resistant fungus that is rapidly spreading …

Candida auris pan-drug-resistant to four classes of antifungal agents

SE Jacobs, JL Jacobs, EK Dennis… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Candida auris is an urgent antimicrobial resistance threat due to its global emergence, high
mortality, and persistent transmissions. Nearly half of C. auris clinical and surveillance cases …

[HTML][HTML] The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris

JM Rybak, CA Cuomo, PD Rogers - Current opinion in microbiology, 2022 - Elsevier
Highlights•C. auris exhibits resistance to multiple antifungal agents and represents a public
health threat.•The molecular mechanisms of antifungal resistance observed in C. auris vary …