[HTML][HTML] Antisense oligonucleotide based therapeutics and its applications against bacterial infections

N Angrish, G Khare - Medicine in Drug Discovery, 2023 - Elsevier
The transcriptome of a cell governs the overall cellular expression of proteins, hence,
targeting mRNA holds promise as a therapeutic strategy in the field of drug discovery. RNA …

Gene therapy as an emerging therapeutic approach to breast cancer: new developments and challenges

M Sheikh-Hosseini, B Larijani… - Human Gene …, 2021 - liebertpub.com
Breast cancer is a heterogeneous disease, which is the consequence of several genetic and
environmental factors. Also, it is one of the most common causes of cancer death and …

Light-triggered cellular delivery of oligonucleotides

LS Kontturi, J Van Den Dikkenberg, A Urtti… - Pharmaceutics, 2019 - mdpi.com
The major challenge in the therapeutic applicability of oligonucleotide-based drugs is the
development of efficient and safe delivery systems. The carriers should be non-toxic and …

Antisense oligonucleotides as therapeutics and their delivery

B Gurav, G Srinivasan - Current Science, 2017 - JSTOR
Antisense oligonucleotides are novel, highly selective inhibitors or modulators of gene
expression. Attention is now being paid for the use of these agents not only in the treatment …

[HTML][HTML] Restoration of correct splicing in IVSI-110 mutation of β-globin gene with antisense oligonucleotides: implications and applications in functional assay …

SM Derakhshan, MS Khaniani - Iranian journal of basic medical …, 2017 - ncbi.nlm.nih.gov
Objective (s): The use of antisense oligonucleotides (AOs) to restore normal splicing by
blocking the recognition of aberrant splice sites by the spliceosome represents an innovative …

Present and future challenges in therapeutic designing using computational approaches

S Prasad, A Srivastava, N Singh, H Singh… - … Approaches for Novel …, 2022 - Elsevier
Currently, various computational methods are being used for the purpose of therapeutic
design. The advent of the Coronavirus disease-2019 (COVID-19) pandemic has created a …

[PDF][PDF] Nanoparticle-based delivery of nucleic acids for targeting multidrug-resistant bacteria

MJ Beha - researchgate.net
Nanoparticle-based delivery of nucleic acids for targeting multidrug-resistant bacteria Page
1 Nanoparticle-based delivery of nucleic acids for targeting multidrug-resistant bacteria …

[PDF][PDF] POTENTIAL ROLE OF ANTISENSE OLIGONUCLEOTIDES IN REGULATION OF GENE EXPRESSION TO TARGET CANCER: A STEP FORWARD

AK Netam, J Prasad, T Satapathy - 2018 - wjpr.s3.ap-south-1.amazonaws.com
WORLD JOURNAL OF PHARMACEUTICAL RESEARCH Page 1 www.wjpr.net Vol 7, Issue 9,
2018. 26 Netam et al. World Journal of Pharmaceutical Research POTENTIAL ROLE OF …

[引用][C] انتقال siRNA ی مربوط به ژن survivin توسط نانوذرات سنتزی جديد به داخل سلول های سرطانی سينه و تعيين اثرات ضد سرطاني نانوپلکس های تهيه شده

آرامی, صنم‎ - دانشگاه علوم پزشکی تبریز، دانشکده …

[引用][C] Delivery of survivin siRNA into breast cancer cell line using new synthetic nanoparticles and determination of the anticancer activity of the nanoplexes

S Arami - 2016 - Tabriz University of Medical …