Nephrons are the functional units which comprise the kidney. Each nephron contains a
number of physiologically unique populations of specialized epithelial cells that are …

Syndromic birth defects are rare diseases that can present with seemingly pleiotropic
comorbidities. Prime examples are rare congenital heart and cardiovascular anomalies that …

Knowledge about the genetic pathways that control nephron development is essential for
better understanding the basis of congenital malformations of the kidney. The transcription …

The glycine cleavage system (GCS) is a complex located on the mitochondrial membrane
that is responsible for regulating glycine levels and contributing one-carbon units to folate …

Endothelial specification is a key event during embryogenesis; however, when, and how,
endothelial cells separate from other lineages is poorly understood. In zebrafish, Npas4l is …

Kidney disease is a devastating condition affecting millions of people worldwide, where over
100,000 patients in the United States alone remain waiting for a lifesaving organ transplant …

Podocytes are exquisitely fashioned kidney cells that serve an essential role in the process
of blood filtration. Congenital malformation or damage to podocytes has dire consequences …

Objectives The odd‐skipped related transcription factor 1 (OSR1) gene exerts distinct
regulatory effects on tumorigenesis and development in various cancer types. However, the …

Knowledge about the genetic pathways that control renal cell lineage development is
essential to better understand the basis of congenital malformations of the kidney and …