Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

The average lifespan of circulating erythrocytes usually exceeds hundred days. Prior to that,
however, erythrocytes may be exposed to oxidative stress in the circulation which could …

Red blood cell (RBC) storage solutions have evolved significantly over the past decades to
optimize the preservation of cell viability and functionality during hypothermic storage. This …

Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …

During the course of their natural ageing and upon injury, anucleate erythrocytes can
undergo an unconventional apoptosis-like cell death, termed eryptosis. Eryptotic …

In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis characterized by
cell shrinkage and cell membrane scrambling. Eryptotic erythrocytes are rapidly cleared …

End stage renal disease (ESRD) invariably leads to anemia which has been mainly
attributed to compromised release of erythropoietin from the defective kidneys with …

Abstract Background Thrombospondin-1 (TSP-1), a Ca 2+-binding trimeric glycoprotein
secreted by multiple cell types, has been implicated in the pathophysiology of several …

Objectives To collect information on pathogen reduction applied to whole blood.
Background Pathogen reduction (PR) of blood components has been developed over the …

Pathogen reduction technologies (PRTs) have been developed to further reduce the current
very low risks of acquiring transfusion‐transmitted infections and promptly respond to …