The contribution of natural products (NPs) to cardiovascular medicine has been extensively
documented, and many have been used for centuries. Cardiovascular disease (CVD) is the …

We report to use the main protease (Mpro) of SARS-Cov-2 to screen plant flavan-3-ols and
proanthocyanidins. Twelve compounds,(–)-afzelechin (AF),(–)-epiafzelechin (EAF),(+) …

Various studies have shown that certain flavonoids, flavonoid-containing plant extracts, and
foods can improve human health. Experimental studies showed that flavonoids have the …

Chronic obstructive pulmonary disease (COPD) with increased morbidity and mortality is a
worldwide healthcare challenge closely associated with cigarette smoking (CS). Currently …

Objectives. We aimed to observe the protective effect of κ opioid receptor (κ‐OR) agonist on
myocardial injury in heart failure (HF) rats and its effect on Ca2+‐SERCA2a and to explore …

Endothelial dysfunction (EnD) occurs with aging and endothelial nitric oxide (NO) production
by NO synthase (NOS) can be impaired. Low NO levels have been linked to increased …

Background Chinese hawthorn (Crataegus pinnatifida) fruit is a traditional Chinese
medicine for treatment of digestive system and cardiovascular diseases. The fruit contains …

Medicinal plants are used in traditional medicine to treat a wide range of ailments. The
knowledge of them is handed down from generation to generation and is described in …

This review summarizes experimental evidence on the beneficial effects of (−)-epicatechin
(EC) attenuating major cardiometabolic risk factors, ie, dyslipidemias, obesity (adipose …

Since the 1970s, the utility of nailfold capillaroscopy (NFC) in diagnosing rheumatological
disorders such as systemic sclerosis has been well established. Further studies have also …