Nephrotic syndrome is a disorder of the kidneys that results from increased permeability of
the glomerular filtration barrier. It is characterized by 4 major clinical characteristics that are …

Focal and segmental glomerulosclerosis (FSGS) is an important cause of steroid-resistant
nephrotic syndrome in adults and children. It is responsible for 5–20% of all cases of end …

Results The overall mutation detection rate was high at 57%(97% in CNS and 41% in
SRNS); 85% of all mutations were identified by the analysis of three single genes only …

BACKGROUND: To examine whether tacrolimus is more effective and safe than
cyclosporine (CsA) in inducing remission in patients with steroid-resistant nephrotic …

Nephrotic syndrome is a disorder characterized by severe proteinuria, hypoproteinemia, and
generalized edema resulting from damage to the glomerular basement membrane. In …

First line immunosuppressive treatment in steroid-resistant nephrotic syndrome in children is
still open to discussion. We conducted a controlled multicentre randomized open label trial …

We conducted a prospective, multicenter trial to evaluate the efficacy and safety of a 12-
month course of cyclosporine in children with steroid-resistant nephrotic syndrome (SRNS) …

Objective High-dose steroid therapy in children is known to impair growth. What is unknown
is the level of steroid therapy at which children continue to grow normally. This study was …

Children with steroid-resistant nephrotic syndrome (SRNS) are at risk of developing renal
failure. We report here the results of a single-center retrospective observational study of the …

Background Calcineurin inhibitor (CNI) use in genetic steroid-resistant nephrotic syndrome
(SRNS) is controversial as response rate is reported to be lower than non-genetic disease …