The assembly of microbial communities within the gastrointestinal tract during early life plays
a critical role in immune, endocrine, metabolic, and other host developmental pathways …

Growth faltering under 5 years of age is unacceptably high worldwide, and even more
children, while not stunted, fail to reach their growth potential. The time between conception …

Background Stunting affects about one-quarter of children under five worldwide. The
pathogenesis of stunting is poorly understood. Nutritional interventions have had only …

Nicotinamide adenine dinucleotide (NAD+) is an essential pyridine nucleotide that serves as
an electron carrier in cellular metabolism and plays a crucial role in the maintenance of …

Background Environmental enteropathy (EE), the adverse impact of frequent and numerous
enteric infections on the gut resulting in a state of persistent immune activation and altered …

Critical to the design and assessment of interventions for enteropathy and its developmental
consequences in children living in impoverished conditions are non-invasive biomarkers …

Mortality in children with severe malnutrition is strongly related to signs of metabolic
dysfunction, such as hypoglycemia. Lower circulating tryptophan levels in children with …

A targeted ultrahigh-performance liquid chromatography tandem mass spectrometry with
electrospray ionization (UHPLC-ESI-MS/MS) method has been developed for the …

Giardia lamblia (Giardia) is among the most common intestinal pathogens in children in low-
and middle-income countries (LMICs). Although Giardia associates with early-life linear …

Nutritional restrictions during the first 1000 days of life can impair or delay the physical and
cognitive development of the individual and have long-term consequences for their health …