Lipid sorting in epithelial cells

K Simons, G Van Meer - Biochemistry, 1988 - ACS Publications
One of the challenges of contemporary cell biology is to unravel how the molecular
composition of the different cellular compartments is generated and maintainedduring the …

Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains

AR Todeschini, S Hakomori - Biochimica et Biophysica Acta (BBA)-General …, 2008 - Elsevier
At cell surface microdomains, glycosyl epitopes, carried either by glycosphingolipids, N-or O-
linked oligosaccharides, are recognized by carbohydrate-binding proteins or …

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

Y Li, D Feng, Z Wang, Y Zhao, R Sun, D Tian… - Cell Death & …, 2019 - nature.com
Ferroptosis is a recently identified form of regulated cell death defined by the iron-dependent
accumulation of lipid reactive oxygen species. Ferroptosis has been studied in various …

Occurrence, absorption and metabolism of short chain fatty acids in the digestive tract of mammals

M Bugaut - Comparative Biochemistry and Physiology Part B …, 1987 - Elsevier
1. Short chain fatty acids (SCFA) also named volatile fatty acids, mainly acetate, propionate
and butyrate, are the major end-products of the microbial digestion of carbohydrates in the …

Lipid rafts and neurodegeneration: structural and functional roles in physiologic aging and neurodegenerative diseases: Thematic review series: Biology of lipid rafts

S Grassi, P Giussani, L Mauri, S Prioni, S Sonnino… - Journal of Lipid …, 2020 - ASBMB
Lipid rafts are small, dynamic membrane areas characterized by the clustering of selected
membrane lipids as the result of the spontaneous separation of glycolipids, sphingolipids …

The organizing potential of sphingolipids in intracellular membrane transport

JCM Holthuis, T Pomorski, RJ Raggers… - Physiological …, 2001 - journals.physiology.org
Eukaryotes are characterized by endomembranes that are connected by vesicular transport
along secretory and endocytic pathways. The compositional differences between the various …

Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane

MJ Gerl, JL Sampaio, S Urban, L Kalvodova… - Journal of Cell …, 2012 - rupress.org
The influenza virus (IFV) acquires its envelope by budding from host cell plasma
membranes. Using quantitative shotgun mass spectrometry, we determined the lipidomes of …

The lipid composition of adult rat brain synaptosomal plasma membranes

WC Breckenridge, G Gombos, IG Morgan - Biochimica et Biophysica Acta …, 1972 - Elsevier
The lipid composition of highly purified synaptosomal plasma membranes has been
analyzed. The membranes contained cholesterol (0.158 mg per mg protein), phospholipids …

Assessing the absorption of new pharmaceuticals

IJ Hidalgo - Current topics in medicinal chemistry, 2001 - ingentaconnect.com
The advent of more efficient methods to synthesize and screen new chemical compounds is
increasing the number of chemical leads identified in the drug discovery phase. Compounds …

Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane?

PR Dragsten, R Blumenthal, JS Handler - Nature, 1981 - nature.com
Membrane-bound lectins and some lipid probes are incapable of passing through the tight
junction region of epithelial cell membranes. The lectins are immobile on the cell surf ace …