CIGB-258 exerts potent anti-inflammatory activity against carboxymethyllysine-induced acute inflammation in hyperlipidemic zebrafish via the protection of …

KH Cho, HS Nam, JE Kim, HJ Na… - International journal of …, 2023 - mdpi.com
Inflammation and atherosclerosis are intimately associated via the production of
dysfunctional high-density lipoproteins (HDL) and modification of apolipoprotein (apo) AI. A …

Long-term supplementation of ozonated sunflower oil improves dyslipidemia and hepatic inflammation in hyperlipidemic zebrafish: Suppression of oxidative stress …

KH Cho, JE Kim, A Bahuguna, DJ Kang - Antioxidants, 2023 - mdpi.com
Ozonated sunflower oil (OSO) is a well-known functional oil with antioxidant, antimicrobial,
anti-allergic, and skin-moisturizing properties. However, studies on the effects of OSO on …

Prey shifts drive venom evolution in cone snails

TL Koch, SD Robinson, PF Salcedo… - Molecular biology …, 2024 - academic.oup.com
Venom systems are complex traits that have independently emerged multiple times in
diverse plant and animal phyla. Within each venomous lineage there typically exists …

Comparison of Policosanols via Incorporation into Reconstituted High-Density Lipoproteins: Cuban Policosanol (Raydel®) Exerts the Highest Antioxidant, Anti …

KH Cho, JE Kim, HS Nam, DJ Kang, SH Baek - Molecules, 2023 - mdpi.com
Reconstituted high-density lipoproteins (rHDL) containing each policosanol from Cuba
(Raydel®), China (Shaanxi Pioneer), and the United States (Lesstanol®) were synthesized …

Single-cell analysis of innate spinal cord regeneration identifies intersecting modes of neuronal repair

VM Saraswathy, L Zhou, MH Mokalled - Nature communications, 2024 - nature.com
Adult zebrafish have an innate ability to recover from severe spinal cord injury. Here, we
report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of …

Cuban Policosanol (Raydel®) Exerts Higher Antioxidant and Anti-Glycation Activities than Chinese Policosanol (BOC Sciences) in Reconstituted High-Density …

KH Cho, JE Kim, MS Lee, A Bahuguna - Pharmaceuticals, 2024 - mdpi.com
The present study compares sugarcane-wax purified policosanols sourced from Cuba
(Raydel®) and China (BOC Sciences) and utilized following the synthesis of reconstituted …

Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish

VM Saraswathy, L Zhou, AR McAdow, B Burris… - Cell reports, 2022 - cell.com
Intrinsic and extrinsic inhibition of neuronal regeneration obstruct spinal cord (SC) repair in
mammals. In contrast, adult zebrafish achieve functional recovery after complete SC …

Progenitor-derived glia are required for spinal cord regeneration in zebrafish

L Zhou, AR McAdow, H Yamada, B Burris… - …, 2023 - journals.biologists.com
Unlike mammals, adult zebrafish undergo spontaneous recovery after major spinal cord
injury. Whereas reactive gliosis presents a roadblock for mammalian spinal cord repair, glial …

Standardization of zebrafish drug testing parameters for muscle diseases

M Karuppasamy, KG English… - Disease Models & …, 2024 - journals.biologists.com
Skeletal muscular diseases predominantly affect skeletal and cardiac muscle, resulting in
muscle weakness, impaired respiratory function and decreased lifespan. These harmful …

Spinal cord injury and assays for regeneration

B Burris, MH Mokalled - Zebrafish: Methods and protocols, 2023 - Springer
Due to their renowned regenerative capacity, adult zebrafish are a premier vertebrate model
to interrogate mechanisms of innate spinal cord regeneration. Following complete …