Neuroinflammation is considered as a detrimental factor in neurodegenerative diseases,
including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) …

The involvement of the central nervous system (CNS) during human acute and chronic
Chagas disease (CD) has been largely reported. Meningoencephalitis is a frequent finding …

Inflammation mediated by the innate immune system is a physiopathological response to
diverse detrimental circumstances such as microbe infections or tissular damage. The …

Current understanding of key cellular pathways, which are activated by the interaction
between T. cruzi and host immunity, is crucial for controlling T. cruzi infection and also for …

Inflammasomes are large protein complexes that, once activated, initiate inflammatory
responses by activating the caspase-1 protease. They play pivotal roles in host defense …

Ginsenosides are a promising group of secondary metabolites for developing anti-
inflammatory agents. In this study, Michael acceptor was fused into the aglycone A-ring of …

Parasites have a significant impact on the neurological, cognitive, and mental well‐being of
humans, with a global population of over 1 billion individuals affected. The pathogenesis of …

Despite the effectiveness of combined antiretroviral therapy (cART) in suppressing virus
replication, chronic inflammation remains one of the cardinal features intersecting HIV-1 …

Background In Chagas disease (CD), a neglected tropical disease caused by the parasite
Trypanosoma cruzi, the development of mental disorders such as anxiety, depression, and …

Introduction: Trypanosoma cruzi is an intracellular protozoa and etiological agent that
causes Chagas disease. Its presence among the immunocompromised HIV-infected …