Inequalities in health outcomes impose substantial human and economic costs on all
societies—and the relation between early adversity and lifelong well-being presents a rich …

Background Although many meta-analyses have examined the association between
childhood sexual abuse and subsequent outcomes, the scope, validity, and quality of this …

Introduction: Adverse childhood experiences (ACE) such as sexual and physical abuse or
neglect are frequent in childhood and constitute a massive stressor with long-lasting …

Abstract Cosponsoring Associations: The European Society of Endocrinology and the
Pediatric Endocrine Society. This guideline was funded by the Endocrine Society. Objective …

Adverse childhood experiences (ACEs) can become biologically embedded leaving a
lasting signature on multiple body systems. ACE scores have been used to associate …

Exposures to adverse environments, both psychosocial and physicochemical, are prevalent
and consequential across a broad range of childhood populations. Such adversity …

Adverse experiences in childhood and adolescence, defined as subjectively perceived
threats to the safety or security of the child's bodily integrity, family, or social structures, are …

It has long been claimed that “maltreatment begets maltreatment,” that is, a parent's history
of maltreatment increases the risk that his or her child will also suffer maltreatment. However …

Children who experience chronic stressors are vulnerable to emotional and physical health
problems across the lifespan. This phenomenon raises questions for scientists and …

Abstract Purpose of Review To explore the sequence and interaction of infancy and early
childhood risk factors, particularly relating to disturbances in the social environment, and …