Osteosarcoma, the most common malignant tumor of the bone, seriously influences people's
lives and increases their economic burden. Conventional chemotherapy drugs achieve …

The modification of surfaces by the deposition of a robust overlayer provides an excellent
handle with which to tune the properties of a bulk substrate to those of interest. Such control …

1. INTRODUCTION The design of organically modified surfaces is a rapidly expanding field
of research in materials science in which the central purpose is access to materials …

R-Aminophosphonic acids are broadly defined as analogues of amino acids in which the
carboxylic group is replaced by a phosphonic acid or related group (usually phosphonous or …

Palaeopathology of Children: Identification of Pathological Conditions in the Human Skeletal
Remains of Non-Adults provides archaeological examples of pathological child remains with …

The ability of bisphosphonates ((HO) 2 P (O) CR 1 R 2 P (O)(OH) 2) to inhibit bone
resorption has been known since the 1960s, but it is only recently that a detailed molecular …

The high concentration of mineral present in bone and pathological calcifications is unique
compared with all other tissues and thus provides opportunity for targeted delivery of …

Osteoporosis, characterized by an imbalance in bone homeostasis, is a global health
concern. Bone defects are difficult to heal in patients with osteoporosis. Classical drug …

Maintaining the stemness of bone marrow mesenchymal stem cells (BMMSCs) is crucial for
bone homeostasis and regeneration. However, in vitro expansion and bone diseases impair …

Although bone tissues possess an intrinsic capacity for repair, there are cases where bone
healing is either impaired or insufficient, such as fracture non-union, osteoporosis …