Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners

T Muramatsu - The journal of biochemistry, 2016 - academic.oup.com
Basigin, also called CD147 or EMMPRIN, is a transmembrane glycoprotein that belongs to
the immunoglobulin superfamily. Basigin has isoforms; the common form (basigin or basigin …

Sugar‐coated sperm: unraveling the functions of the mammalian sperm glycocalyx

E Tecle, P Gagneux - Molecular reproduction and development, 2015 - Wiley Online Library
Mammalian spermatozoa are coated with a thick glycocalyx that is assembled during sperm
development, maturation, and upon contact with seminal fluid. The sperm glycocalyx is …

How, with whom and when: an overview of CD147-mediated regulatory networks influencing matrix metalloproteinase activity

GD Grass, BP Toole - Bioscience Reports, 2016 - portlandpress.com
Matrix metalloproteinases (MMPs) comprise a family of 23 zinc-dependent enzymes
involved in various pathologic and physiologic processes. In cancer, MMPs contribute to …

[HTML][HTML] CD147 and MMPs as key factors in physiological and pathological processes

R Asgari, A Vaisi-Raygani, MSE Aleagha… - Biomedicine & …, 2023 - Elsevier
Abstract Cluster of differentiation 147 (CD147) or extracellular matrix metalloproteinase
inducer (EMMPRIN) is a transmembrane glycoprotein that induces the synthesis of matrix …

Importance of N-Glycosylation on CD147 for Its Biological Functions

Y Bai, W Huang, LT Ma, JL Jiang, ZN Chen - International journal of …, 2014 - mdpi.com
Glycosylation of glycoproteins is one of many molecular changes that accompany malignant
transformation. Post-translational modifications of proteins are closely associated with the …

TMT-based quantitative proteomic analysis of porcine muscle associated with postmortem meat quality

X Hou, Q Liu, Q Meng, L Wang, H Yan, L Zhang… - Food Chemistry, 2020 - Elsevier
To explore the molecular mechanisms of meat quality, four high-quality (HQ) samples and
four low-quality (LQ) samples from longissimus dorsi muscles were chosen, and tandem …

Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice

XH Jiang, I Bukhari, W Zheng, S Yin… - Asian journal of …, 2014 - journals.lww.com
The blood-testis barrier (BTB) is found between adjacent Sertoli cells in the testis where it
creates a unique microenvironment for the development and maturation of meiotic and …

Ptbp2 controls an alternative splicing network required for cell communication during spermatogenesis

MM Hannigan, LL Zagore, DD Licatalosi - Cell reports, 2017 - cell.com
Alternative splicing has essential roles in development. Remarkably, spermatogenic cells
express more alternatively spliced RNAs compared to most whole tissues; however …

The role of basigin in reproduction

K Li, RA Nowak - Reproduction, 2020 - rep.bioscientifica.com
Basigin is a highly glycosylated transmembrane protein that was originally identified as a
product of tumor cells. Basigin is a potent inducer of matrix metalloproteinases (MMPs) and …

Role of CD147 (EMMPRIN/Basigin) in tissue remodeling

D Guindolet, EE Gabison - The Anatomical Record, 2020 - Wiley Online Library
ABSTRACT CD147, also known as extracellular matrix metalloproteinase inducer
(EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation …