Ischemic stroke is a leading cause of death worldwide. A key secondary cell death
mechanism mediating neurological damage following the initial episode of ischemic stroke …

Systemic or intracerebral delivery of neural stem and progenitor cells (NSPCs) and
activation of endogenous NSPCs hold much promise as potential treatments for diseases in …

To model human neural-cell-fate specification and to provide cells for regenerative
therapies, we have developed a method to generate human neural progenitors and neurons …

In recent years, stem cell‐based approaches have attracted more attention from scientists
and clinicians due to their possible therapeutical effect on stroke. Animal studies have …

Compelling evidence from experimental animal disease models and early-phase clinical
trials identifies the transplantation of neural progenitor/stem cells (NSCs) as a viable path …

Cell-based therapies represent a new therapeutic approach for stroke. In 2007, investigators
from academia, industry leaders, and members of the National Institutes of Health crafted …

Cell therapies are increasingly recognized as a promising option to augment the limited
therapeutic arsenal available to fight ischemic stroke. During the last two decades …

Human induced pluripotent stem cells (iPSCs) are promising in regenerative medicine.
However, the risks of teratoma formation and the overgrowth of the transplanted cells …

Stem cell-based approaches hold much promise as potential novel treatments to restore
function after stroke. Studies in animal models have shown that stem cell transplantation can …

Transplantation of neural stem cells (NSCs) offers a novel therapeutic strategy for stroke;
however, massive grafted cell death following transplantation, possibly due to a hostile host …