Clinical management of metastatic colorectal cancer in the era of precision medicine

F Ciardiello, D Ciardiello, G Martini… - CA: a cancer journal …, 2022 - Wiley Online Library
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …

Increasing incidence of early-onset colorectal cancer

FA Sinicrope - New England Journal of Medicine, 2022 - Mass Medical Soc
Early-Onset Colorectal Cancer Early-onset disease (at< 50 years of age) accounts for 10%
of colorectal cancer cases, and the incidence is increasing, particularly in high-income …

2020 全球癌症统计报告解读

刘宗超, 李哲轩, 张阳, 周彤, 张婧莹, 游伟程… - 肿瘤综合治疗电子 …, 2021 - jmcm2018.com
2021 年1 月, 国际癌症研究机构团队在美国癌症学会旗下权威杂志《 临床医师癌症杂志》(CA: A
Cancer Journal for Clinicians) 发表了最新的全球癌症统计报告. 该报告阐述了2020 年36 …

Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN

E Morgan, M Arnold, A Gini, V Lorenzoni, CJ Cabasag… - Gut, 2023 - gut.bmj.com
Objective Colorectal cancer (CRC) is the third most common cancer worldwide. The
geographical and temporal burden of this cancer provides insights into risk factor …

Rectal cancer, version 2.2022, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary, N Azad… - Journal of the National …, 2022 - jnccn.org
This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

PD-1 blockade in mismatch repair–deficient, locally advanced rectal cancer

A Cercek, M Lumish, J Sinopoli, J Weiss… - … England Journal of …, 2022 - Mass Medical Soc
Background Neoadjuvant chemotherapy and radiation followed by surgical resection of the
rectum is a standard treatment for locally advanced rectal cancer. A subset of rectal cancer is …

Cancer statistics for African American/black people 2022

AN Giaquinto, KD Miller, KY Tossas… - CA: a cancer journal …, 2022 - Wiley Online Library
Abstract African American/Black individuals have a disproportionate cancer burden,
including the highest mortality and the lowest survival of any racial/ethnic group for most …

Cancer statistics for A merican I ndian and A laska N ative individuals, 2022: Including increasing disparities in early onset colorectal cancer

TB Kratzer, A Jemal, KD Miller, S Nash… - CA: A Cancer …, 2023 - Wiley Online Library
Abstract American Indian and Alaska Native (AIAN) individuals are diverse culturally and
geographically but share a high prevalence of chronic illness, largely because of obstacles …

[HTML][HTML] Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis

J Cai, L Sun, FJ Gonzalez - Cell host & microbe, 2022 - cell.com
Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are heterogeneous intestinal
diseases that threaten the health of an increasing number of individuals as their lifestyles …

Current and future colorectal cancer screening strategies

A Shaukat, TR Levin - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Despite strong evidence of effectiveness, colorectal cancer (CRC) screening remains
underused. Currently, there are several options for CRC screening, each with its own …